PMID: 6171128Jul 1, 1981Paper

Relationships between metabolic and hemostatic variables in uncomplicated diabetes

Acta diabetologica latina
C VerganiP M Mannucci

Abstract

Several metabolic (HbA1, HDL-C, triglycerides) and hemostatic (VIIIR: Ag, VIII:C, B-TG variables were investigated in 35 non-obese, insulin-dependent diabetics without clinically evident vascular complications. B-TG was high but did not correlate with other metabolic and hemostatic parameters, suggesting that elevated B-TG in diabetes might be an expression of in vitro platelet activation. VIIIR: Ag and the ratio of VIIIR: Ag to VIII: C were markedly increased. There was a significant correlation of the HbA1 and HDL-C levels with VIIIR: Ag, indicating that VIIIR:Ag is another reflection of metabolic control in diabetes. Additional pathogenic mechanisms, however, appear to be involved in causing the changes in VIIIR: Ag in diabetes.

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Citations

Jun 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·P Chan, W H Pan

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