Relationships between the lung-heart ratio assessed from post-exercise thallium-201 myocardial tomograms, myocardial ischemia and the extent of coronary artery disease

International Journal of Cardiac Imaging
B IlmerP M Fioretti

Abstract

Uptake of thallium (Tl)-201 in the lungs has been proposed as a measure of left ventricular dysfunction. In this study we were interested in pursuing two goals: 1) to assess possible relationships between the post-exercise Tl-201 lung-heart (LH)-ratio determined from the anterior view during SPECT-acquisition, myocardial ischemia and the extent of coronary artery disease; and 2) to explore the effects of coronary revascularisation procedures on the LH-ratio. The study group consisted of 145 patients with early and late postexercise Tl-201 tomograms, including 32 PTCA-patients with pre- and post-PTCA studies and 20 patients who underwent coronary artery bypass surgery (CABG) with corresponding pre- and post-CABG studies. Ischemia was defined as evoked angina during the exercise test in combination with greater than or equal to 1 mm horizontal or downsloping ST-depression on the ECG. The severity of coronary obstructions was assessed from coronary angiograms with a PC-based digital caliper technique; a stenosis was defined to be significant when its severity exceeded 50% diameter stenosis. The LH-ratio was defined by the ratio of the mean pulmonary counts and the mean myocardial counts assessed from corresponding regions of inter...Continue Reading

References

Jan 1, 1991·International Journal of Cardiac Imaging·G KoningB van Meurs
Feb 1, 1982·AJR. American Journal of Roentgenology·N TamakiC Kawai
Oct 1, 1983·Journal of the American College of Cardiology·R LevyH J Swan
Nov 1, 1980·The American Journal of Cardiology·J B BinghamG M Pohost

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Citations

Oct 16, 2003·Biological Reviews of the Cambridge Philosophical Society·Wilfrida DecraemerThierry Backeljau
Jan 8, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Leopoldo Pérez de IslaCarlos Macaya
Nov 1, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Aiden Abidov
Jul 30, 2002·Proceedings of the National Academy of Sciences of the United States of America·Turhan CanliJohn D E Gabrieli

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