PMID: 11934653Apr 6, 2002Paper

Relationships between trabecular bone remodeling and bone vascularization: a quantitative study

Bone
O BarouM H Lafage-Proust

Abstract

Beside its well-known role in bone development, vascularization plays a major role in bone cell migration for bone remodeling and metastatic tumor invasion. However, the various techniques used to identify vessels in bone have never been tested for trabecular bone vessel quantification, whereas bone remodeling quantitative parameters are commonly assessed. In this context, we developed and compared various histological techniques used to visualize blood vessels in rat bone in order to quantify them. First, several products were tested by intracardiac infusion to opacify the bone vascular network. The best results were obtained using either an India ink-1% agarose solution or an India ink-saturated barium sulfate solution followed by X-ray microradiography. Second, to identify the types of vessels, we also performed histoenzymology and immunohistochemistry stainings. Neither alkaline phosphatase (for endothelial cells) nor adenosine triphosphatase (ATPase) stainings (for smooth muscle cells) provided a low enough background to allow for vessel identification and quantification. For immunohistochemistry, various specific vessel constituents were analyzed: laminin, smooth muscle cell alpha-actin, factor VIII, and lectin Griffonia ...Continue Reading

References

Dec 1, 1992·Journal of Dental Research·N BlaushildS Steigman
Jun 1, 1992·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·E LuqueI Jimena
Jun 1, 1992·The Anatomical Record·L de Saint-Georges, S C Miller
Aug 1, 1992·The Anatomical Record·D Lewinson, M Silbermann
Oct 1, 1991·The Anatomical Record·R Hamilton, F R Campbell
Sep 1, 1970·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M H Brooke, K K Kaiser
Jan 1, 1980·Acta Anatomica·G Marotti, A Z Zallone
Jul 1, 1994·Journal of Cellular Biochemistry·P Collin-Osdoby
Sep 1, 1996·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·E F MurrellR B Johnson
Sep 1, 1997·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·O BarouM H Lafage-Proust
Apr 29, 1998·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S K NilssonP S Becker
Oct 12, 1999·Endocrine-related Cancer·B F BoyceT A Guise
Nov 26, 1999·Journal of Pediatric Orthopedics·B FinkW Rüther
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M Yi, E Ruoslahti
Mar 27, 2001·Journal of Cellular Physiology·A M Kitten, C J Andrews

❮ Previous
Next ❯

Citations

Jun 7, 2007·Calcified Tissue International·Hironori MatsuzakiMatthew J Silva
Apr 12, 2006·Clinical Oral Investigations·Tonino TrainiAdriano Piattelli
Nov 3, 2010·Acta Pharmacologica Sinica·Elisabetta CenniNicola Baldini
Nov 8, 2008·Acta Histochemica Et Cytochemica·Tong JianbinLuo Xuegang
Oct 29, 2010·Joint, Bone, Spine : Revue Du Rhumatisme·Marie-Hélène Lafage-ProustLaurence Vico
Dec 29, 2013·Cell and Tissue Banking·N M C MathijssenG Hannink
Jul 19, 2014·Archives of Biochemistry and Biophysics·Uttara SaranSuvro Chatterjee
Nov 6, 2007·Joint, Bone, Spine : Revue Du Rhumatisme·Marie-Hélène VieillardBernard Cortet
May 15, 2008·Journal of Biomedical Materials Research. Part a·Mark R ApplefordJoo L Ong
Jan 22, 2008·Clinical Implant Dentistry and Related Research·Tonino TrainiAdriano Piattelli
Sep 20, 2012·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Helene Bjoerg KristensenJean-Marie Delaisse
Dec 4, 2009·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Jia FeiLafage-Proust Marie-Hélène
Aug 18, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Zhenqiang YaoLaurence Vico
Sep 12, 2008·Clinical Implant Dentistry and Related Research·Danilo Alessio Di StefanoVittoria Perrotti
May 9, 2015·Calcified Tissue International·Guillaume MichelFlorent Espitalier
Mar 5, 2015·Clinical Orthopaedics and Related Research·Hanxiao ZhuShigui Yan
Sep 2, 2014·The American Journal of Chinese Medicine·Yun-Liang CuiDe-Chang Chen
Aug 16, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Marta Cavo, Silvia Scaglione
Jan 5, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Wensheng WangLianping Xing
Feb 17, 2018·Connective Tissue Research·Jian ZhangGuangming Zhou
Jul 10, 2013·Laboratory Investigation; a Journal of Technical Methods and Pathology·Takeshi MatsumotoSyota Sato
Nov 6, 2018·Biomechanics and Modeling in Mechanobiology·Toshihiro SeraMasao Tanaka
Jan 31, 2015·Journal of Applied Physiology·Rhonda D PrisbyMichael D Delp
Sep 5, 2003·The Journal of Biological Chemistry·Olivier PeyruchaudPhilippe Clezardin
Aug 1, 2015·Journal of Applied Physiology·Vasily GnyubkinLaurence Vico
Jan 7, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Zbisław TaborTadeusz Cichocki
Sep 3, 2021·Journal of Applied Physiology·Joshua F YarrowDanielle J McCullough
May 22, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Chuan ZhangKevin K McCully

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.