PMID: 2506357Sep 1, 1989Paper

Relationships of the chromosomal species in the Eurasian mole rats of the Spalax ehrenbergi group as determined by DNA-DNA hybridization, and an estimate of the spalacid-murid divergence time

Journal of Molecular Evolution
F M CatzeflisC G Sibley

Abstract

DNA-DNA hybridization was used to measure the average genomic divergence among the four chromosomal species of the Eurasian mole rats belonging to the Spalax ehrenbergi complex (Rodentia: Spalacidae). The percent nucleotide substitutions in the single-copy nuclear DNA among the species ranged from 0 to 5%, suggesting that speciation has occurred with minor genomic changes in these animals. The youngest chromosomal species appear to differ by 0.2-0.6% base pair mismatch, which is only between one and three base differences in a 500-bp fragment. The interspecific values of percent nucleotide differences permit the recognition of two well-separated speciation events in the S. ehrenbergi complex, the older (of Lower Pleistocene age) having isolated the chromosomal species 2n = 54 before the divergence of the three other species. DNA-DNA hybridization was also used to compare the Spalacinae (Eurasian mole rats), Murinae (Old World rats and mice), and Arvicolinae (voles and lemmings). These data enabled us to estimate the time of divergence of the spalacids at ca. 19 million years ago. The dates of divergence among the other rodent lineages, as predicted by DNA hybridization results, agree well with paleontological data. These dates ...Continue Reading

References

Sep 14, 1978·Nature·E Nevo, H Cleve
Sep 12, 1985·Nature·S J O'BrienR E Benveniste
Dec 5, 1973·Journal of Molecular Biology·T I BonnerR J Britten
Jan 1, 1974·Methods in Enzymology·R J BrittenB R Neufeld
Feb 14, 1968·Journal of Molecular Biology·J G Wetmur, N Davidson
Jan 1, 1968·Journal of Neurosurgery·B W BrawleyW A Kelly
Jan 1, 1984·Journal of Molecular Evolution·C G Sibley, J E Ahlquist
Sep 23, 1983·Science·M C McKenna
Dec 1, 1976·Evolution; International Journal of Organic Evolution·Eviatar Nevo, Hana Bar-El
Mar 1, 1981·Evolution; International Journal of Organic Evolution·Giora Heth, Eviatar Nevo
Sep 1, 1983·Evolution; International Journal of Organic Evolution·Elise Brownell

❮ Previous
Next ❯

Citations

Nov 15, 1995·Molecular & General Genetics : MGG·H SezutsuT Yamazaki
Jan 1, 1987·Immunogenetics·T BlankensteinU Krawinkel
Dec 1, 1993·Mammalian Genome : Official Journal of the International Mammalian Genome Society·P Garcia-MeunierF Bonhomme
Jan 1, 1987·Journal of Molecular Evolution·T H Jukes
Jan 30, 2013·Proceedings of the National Academy of Sciences of the United States of America·Yarin HadidEviatar Nevo
Feb 1, 1990·Immunological Reviews·F FigueroaJ Klein
Jun 15, 2013·Science·Scott MircetaMichael Berenbrink
Jan 19, 2012·PloS One·Yarin HadidEviatar Nevo
Nov 16, 2005·Proceedings of the National Academy of Sciences of the United States of America·L I BrodskyE Nevo
Nov 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·A AviviE Nevo
May 22, 2013·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Lucy GonthierMarie-Christine Quillet
Jul 1, 1997·Pediatric Rehabilitation·G Baltaci, N Ergun
Apr 26, 2003·Molecular Genetics and Genomics : MGG·Y KoikeT Shimada
Feb 1, 1992·Evolution; International Journal of Organic Evolution·Robin M Bush, Kenneth Paigen
Dec 6, 2020·Proceedings of the National Academy of Sciences of the United States of America·Kexin LiEviatar Nevo
Feb 15, 1993·The Journal of Comparative Neurology·H M CooperE Nevo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.