PMID: 6403686Feb 1, 1983Paper

Relative conversion of arachidonic acid through lipoxygenase and cyclooxygenase pathways by homogenates of diseased periodontal tissues

Journal of Oral Pathology
T M El Attar, H S Lin

Abstract

The present study shows that 14C-arachidonic acid metabolism in gingiva of patients with periodontal disease is mainly via the lipoxygenase pathway. In two pools of gingival tissue homogenates, the lipoxygenase products contained 22.65% and 23.38%, while the prostaglandins (PGs), products of the cyclooxygenase pathway, contained only 4.85% and 3.98% of the total radioactivity incubated. 12-hydroxy-eicosatetraenoic acid (12-HETE), a lipoxygenase product, was detected as a major metabolite of arachidonic acid in gingiva.

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Citations

Mar 1, 1990·Agents and Actions·S OffenbacherF J Sena
Sep 1, 1991·Calcified Tissue International·W Ren, R Dziak
Oct 20, 1992·European Journal of Pharmacology·M H Yen, C S Lai
Jan 1, 1987·The International Journal of Biochemistry·E MalleG M Kostner
Jun 1, 1986·Prostaglandins, Leukotrienes, and Medicine·M A LazzariM Gimeno
Nov 1, 1993·Journal of Clinical Periodontology·T B Taiyeb Ali, I M Waite
Jan 1, 1985·Journal of Periodontology·C F MendietaJ C Romero
Sep 26, 2002·Journal of Periodontology·Marinella HolzhausenLuis C Spolidório
May 1, 1992·Journal of Endodontics·M TorabinejadT Jung
Jan 1, 1990·Archives of Oral Biology·K TamaiA Tsujimoto
Mar 1, 1986·Journal of Periodontal Research·T M elAttarJ M Goodson
Mar 1, 1986·Journal of Periodontal Research·S OffenbacherT E Van Dyke
May 1, 1986·Oral Surgery, Oral Medicine, and Oral Pathology·R K White, S Montgomery
Aug 1, 1984·Journal of Maxillofacial Surgery·H PortederH Sinzinger
Jul 19, 2016·Oral Diseases·S Sommakia, O J Baker
Mar 1, 1994·International Endodontic Journal·E Cotti, M Torabinejad
Jun 1, 1985·The British Journal of Oral & Maxillofacial Surgery·M MatejkaH Sinzinger
Dec 1, 1991·Endodontics & Dental Traumatology·M TorabinejadG Lessard
Jan 1, 1993·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·T H Howell, R C Williams
Jan 1, 1994·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·B S McAllisterM S Olson
Nov 24, 1998·Infection and Immunity·F Nichols, B Maraj

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