PMID: 7541460Apr 1, 1995Paper

Relative degree of stimulation-evoked glycogen degradation in muscle fibres of different type in rat gastrocnemius

The Journal of Physiology
D KernellA de Haan

Abstract

1. The relative degree of glycogen degradation, caused in different fibre types by supramaximal electrical activation of the muscle nerve, was investigated in m. gastrocnemius medialis of young adult rats under general pentobarbitone anaesthesia. Four different protocols of intermittent maximal tetanic activation were used, each lasting 6 s (33% duty cycle; fast and slow isovelocity concentric (shortening) contractions, brief- and long-burst isometric contractions; 6 rats per group). All contractions were evoked under ischaemic conditions. 2. Work output finally dropped to 29% of the initial value for the fast concentric and to 87% for the slow concentric contractions. In isometric protocols evoked by the same stimulation patterns, the force x time area rose to 110% for brief-burst contractions and dropped to 95% for the long-burst contractions. 3. Following the physiological procedures, the experimental muscle and its contralateral control were removed and prepared for histochemical analysis. Serial sections were stained for glycogen (periodic acid-Schiff (PAS) method) and myofibrillar ATPase (mATPase), the latter reactions being used for classifying the fibres as types I, IIA, IIBd and IIBm. 4. For deep 'red' regions of non-s...Continue Reading

Citations

Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·A de HaanE Verburg
May 6, 2008·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·P KaczmarekA Kasiński
May 12, 2005·Journal of Vascular Surgery·Christopher D AskewMark A Febbraio
Sep 5, 2002·Muscle & Nerve·Cheryl R BillanteR E Stone
Feb 13, 2019·American Journal of Physiology. Endocrinology and Metabolism·Mark W PatakyGregory D Cartee
Sep 8, 2007·Journal of Applied Physiology·T M AltenburgA de Haan
Jul 21, 2009·Molecular and Cellular Biochemistry·M LjubisavljevicN Nagelkerke

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