Relative mortality rates from incident chronic diseases among breast cancer survivors--a 14 year follow-up of five-year survivors diagnosed in Denmark between 1994 and 2007

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Anne Gulbech OrdingTimothy L Lash

Abstract

It remains unknown whether incident chronic diseases are more often fatal among breast cancer survivors than among women free of breast cancer. We conducted a nationwide matched cohort study of all Danish breast cancer patients diagnosed between 1994 and 2007, who survived for five years. We compared their long-term mortality with five times as many women from the general population without breast cancer, matched on age. We used time-varying methods to compute mortality rate ratios (MRRs) for incident diseases included in the Charlson Comorbidity Index (CCI). One third of five-year breast cancer survivors developed incident diseases during 14 years of follow-up, with about the same incidence as women without breast cancer. Mortality associated with any incident disease was similar among breast cancer survivors (MRR = 7.1, 95% confidence interval (CI): 6.7, 7.4) and comparison women (MRR = 7.5, 95% CI: 7.3, 7.7). Among breast cancer patients, relative mortality associated with incident diseases was higher among patients treated with chemotherapy (MRR = 10, 95% CI: 8.7, 12) and radiotherapy (MRR = 9.8, 95% CI: 8.8, 11) than among patients who received surgery (MRR = 7.0, 95% CI: 6.7, 7.4) or hormonal therapy (MRR = 6.3, 95% CI: 5...Continue Reading

References

Aug 27, 2002·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·A R JensenH H Storm
Mar 15, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·W J LouwmanJ W W Coebergh
Mar 23, 2007·Breast Cancer Research and Treatment·Isabelle SoerjomataramJan Willem W Coebergh
May 14, 2009·Journal of Cancer Survivorship : Research and Practice·Linda C HarlanRachel Ballard-Barbash
Feb 4, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H A AzimM J Piccart
Jul 2, 2011·Journal of the National Cancer Institute·Jennifer L PatnaikDana Dabelea
Aug 4, 2011·Scandinavian Journal of Public Health·Carsten Bøcker Pedersen
Aug 4, 2011·Scandinavian Journal of Public Health·Elsebeth LyngeMatejka Rebolj
Aug 4, 2011·Scandinavian Journal of Public Health·Marianne Lundkjær Gjerstorff
Oct 13, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alistair RingJack Cuzick
Oct 18, 2011·Breast Cancer Research and Treatment·Lotte Holm LandMarianne Ewertz
Nov 1, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M D DaneseR I Griffiths
Jul 26, 2012·Breast Cancer Research and Treatment·Anders BerglundMats Lambe
Mar 26, 2013·Pharmacoepidemiology and Drug Safety·Steven M BrunelliJohn D Seeger
Nov 10, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M L G Janssen-HeijnenD J van Spronsen
Mar 4, 2014·Breast Cancer Research and Treatment·Timothy L LashRebecca A Silliman
Mar 13, 2014·Journal of Geriatric Oncology·Monika IzanoDejana Braithwaite

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Citations

Mar 8, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Rebecca L SedjoCheryl L Rock
Oct 25, 2016·International Journal of Cardiology·Mariana Romanholi PalmaCristina Elena Prado Teles Fregonesi
Jan 16, 2021·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Elizabeth J SiembidaRoxanne E Jensen

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