Relay catalysis: combined metal catalyzed oxidation and asymmetric iminium catalysis for the synthesis of bi- and tricyclic chromenes

Chemical Communications : Chem Comm
Magnus RuepingModhu Sudan Maji

Abstract

A catalytic asymmetric oxidative iminium-allenamine cascade allows the use of propargyl alcohols as stable substrates and yields valuable chiral bicyclic 4H-chromenes. A subsequent Michael addition-condensation domino reaction provides complex tricyclic 4H-chromenes in a highly enantioselective fashion.

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Citations

Jan 13, 2017·Organic Letters·Samrat SahuModhu Sudan Maji
Nov 22, 2014·Chemical Communications : Chem Comm·Seema Dhiman, S S V Ramasastry
Nov 17, 2012·Chemical Society Reviews·Zhenting Du, Zhihui Shao
Oct 17, 2014·The Journal of Organic Chemistry·Zhi-Cong GengXing-Wang Wang
Oct 9, 2012·Organic Letters·Daniel KönningMathias Christmann

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