Release and protein binding of components from resin based composites in native saliva and other extraction media

Dental Materials : Official Publication of the Academy of Dental Materials
Lena RothmundChristof Högg

Abstract

Unpolymerized (co)monomers and additives can be released from resin based composites (RBCs) and can enter the human organism. In this study, the binding of ingredients from composites to salivary proteins and plasma proteins was investigated. The composites investigated were Admira(®) flow, Venus(®) Diamond flow, Filtek™ Supreme XTE flow, Tetric EvoCeram(®), Tetric EvoFlow(®). The samples (n=4) were polymerized according to the instructions of the manufacturer of RBCs. The samples were immersed into native saliva, protein-free saliva (artificial saliva), water and ethyl acetate, and incubated at 37°C for 24h or 72h. The eluates were analyzed by gas chromatography/mass spectrometry. To determine the binding to salivary proteins, the concentration of (co)monomers and additives detected in native saliva was compared to the concentration of (co)monomers and additives detected in protein-free saliva, water and ethyl acetate respectively. To assess the affinity of TEGDMA, EGDMA, DEGDMA, PMGDMA, BPA, and DCHP to human serum albumin (HSA) and human α1-acid glycoprotein (AGP), a plasma protein binding assay (ABNOVA, Transil XL PPB Prediction Kit TMP-0212-2096) was performed. The statistical significance (p<0.05) of the difference betwee...Continue Reading

References

Oct 1, 1990·Dental Materials : Official Publication of the Academy of Dental Materials·J L Ferracane, J R Condon
Sep 1, 1973·Archives of Oral Biology·E Benedek-Spät
Oct 1, 1984·Journal of Dental Research·K J SöderholmM Bergman
Dec 1, 1982·Journal of Pharmaceutical Sciences·J Blanchard
Jul 1, 1994·Journal of Oral Rehabilitation·T M Gerzina, W R Hume
Feb 1, 1993·Acta Odontologica Scandinavica·H LygreE Berg
Jan 1, 1995·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J D Rudney
Nov 22, 1997·The Journal of the American Dental Association·D NathansonL L Chou
Oct 6, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·W Geurtsen
Jan 17, 2002·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Yui YamamotoTsuyoshi Yokoi
Oct 19, 2002·Dental Materials : Official Publication of the Academy of Dental Materials·Franz-Xaver ReichlWyatt Hume
Jan 18, 2005·Journal of Dentistry·S SchwengbergF X Reichl
Mar 8, 2005·Drug Metabolism Reviews·Shufeng ZhouYu-Zong Chen
May 6, 2005·Clinical Oral Investigations·Mihaela Roxana CimpanHenning Lygre
Feb 7, 2006·Dental Materials : Official Publication of the Academy of Dental Materials·Mario SeissFranz X Reichl
Feb 24, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Uwe FuhrEdgar Schömig
Sep 26, 2006·Journal of Dental Research·H SchweiklG Schmalz
Jan 4, 2007·Journal of Materials Science. Materials in Medicine·K MoharamzadehA M Scutt
Jul 6, 2007·Archives of Toxicology·Franz-Xaver ReichlReinhard Hickel
Aug 4, 2007·Chemical Research in Toxicology·T Wayne SchultzAynur O Aptula
Sep 25, 2007·Dental Materials : Official Publication of the Academy of Dental Materials·Vibeke B MichelsenHenning Lygre
Jan 14, 2009·Biomaterials·Alexander EckhardtHelmut Schweikl
Jan 16, 2009·Biomaterials·J DurnerFranz X Reichl
Sep 1, 2009·Dental Materials : Official Publication of the Academy of Dental Materials·Joachim VolkWerner Geurtsen
Sep 22, 2009·Dental Materials : Official Publication of the Academy of Dental Materials·Ebru UrcanFranz Xaver Reichl
Sep 29, 2009·Dental Materials : Official Publication of the Academy of Dental Materials·Jürgen DurnerFranx-Xaver Reichl
Oct 17, 2009·Biomaterials·Jürgen DurnerFranz-Xaver Reichl
Apr 1, 2010·Dental Materials : Official Publication of the Academy of Dental Materials·J DurnerF X Reichl
Sep 9, 2010·Dental Materials : Official Publication of the Academy of Dental Materials·Franz-Xaver ReichlJürgen Durner
Sep 29, 2011·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Olga PolydorouKlaus Kümmerer
Nov 10, 2012·International Endodontic Journal·C Di NisioV di Giacomo
Jun 27, 2013·Journal of Pharmaceutical Sciences·Tonika Bohnert, Liang-Shang Gan
Jul 23, 2013·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Raghuwar D SinghSunit K Jurel
Dec 21, 2013·International Endodontic Journal·M GalloriniV di Giacomo
Mar 22, 2014·Dental Materials : Official Publication of the Academy of Dental Materials·Marija SevkusicFranz-Xaver Reichl

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Citations

Jan 23, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Anand V Susila, Venkatesh Balasubramanian
Sep 9, 2015·Dental Materials : Official Publication of the Academy of Dental Materials·Simon Daniel SchulzOlga Polydorou
Jun 28, 2016·Clinical Oral Investigations·Sina HeimerBogna Stawarczyk
Nov 12, 2016·Dental Materials : Official Publication of the Academy of Dental Materials·Lena RothmundChristof Högg
Jul 28, 2017·Dental Materials Journal·Panorea StyllouHarry Scherthan
Oct 21, 2016·Clinical Oral Investigations·Christof HöggFranz-Xaver Reichl
Mar 3, 2021·Dental Materials : Official Publication of the Academy of Dental Materials·Lennart WedekindChristof Högg
Mar 11, 2018·Dental Materials : Official Publication of the Academy of Dental Materials·Nancy J LinSheng Lin-Gibson
Sep 26, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Andreas KesslerChristof Högg
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Konstantina RoussouElisabeth A Koulaouzidou

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