Release behavior of cupric ions for TCu380A and TCu220C IUDs

Biomedical Materials
Bianmei CaoYudong Zheng

Abstract

We immersed copper T380A and T220C IUDs in simulated uterine solution (SUS) and also in simulated body fluid (SBF). The release rate and corrosion products of copper ions after soaking in SUS and SBF for different time spans were studied by an atomic absorption spectrophotometer, scanning electron microscopy with energy dispersive x-ray microanalysis (SEM/EDX) and x-ray diffraction. The highest corrosion rate of the TCu380A IUD was obtained on the first day, while the highest corrosion rate of the TCu220C IUD was obtained on the third day. The copper corrosion rate of the TCu380A IUD was much faster than that of the TCu220C IUD in the first few days. The corrosion extent of copper wire was higher than that of a copper tube when first immersed in solution. For the same IUD in the same solution, the corrosion extent in SBF was higher than in SUS. The main compounds identified were cuprite (Cu(2)O). Copper wire and copper tubes were implanted in the uteruses of rats. In vivo experiments were also done. The corrosion rate in vivo was higher than that in vitro.

References

Mar 1, 1990·Journal of Biomedical Materials Research·T KokuboT Yamamuro
Dec 15, 1969·American Journal of Obstetrics and Gynecology·J A ZipperM Rivera
Nov 20, 1998·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·H XueC Zhang
Aug 26, 2000·Contraception·J M BastidasN Mora
Oct 6, 2000·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·J ZhuC Zhang
Sep 7, 2004·Journal of Materials Science. Materials in Medicine·J M BastidasJ L Polo
Dec 9, 2004·Biomaterials·Shuizhou CaiChangsheng Xie
Sep 9, 2005·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·D M BastidasE M Mora
Aug 21, 2007·Contraception·Juan LiXiwang Wu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.