PMID: 871862Jul 30, 1977Paper

Release of copper from copper-bearing intrauterine contraceptive devices

British Medical Journal
E ChantlerM Elstein


We measured the rate of release from copper-bearing intrauterine contraceptive devices (IUDs) with varying copper surface areas. Over 135 days of observation the release rate decreased exponentially. This decrease in the release rate was associated with the deposition of a protein layer on the surface of the metal. The bioavailability of copper on IUDs was not related to the volume of copper remaining on the device. Consequently any increase in the copper surface area of an IUD is unlikely to affect the duration of its copper-dependent contraceptive action.


Dec 1, 1994·Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception·E ChantlerM Elstein
Sep 1, 1982·Contraception·M ThieryH J Tatum
Sep 1, 1982·British Journal of Obstetrics and Gynaecology·J R Newton
Aug 26, 2004·Dermatologic Therapy·Jurij J Hostynek, Howard I Maibach
Feb 1, 1984·British Journal of Obstetrics and Gynaecology·E ChantlerI Brough
Jan 1, 1980·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J Guillebaud
Dec 16, 2003·Reviews on Environmental Health·Jurij J Hostynek, Howard I Maibach

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Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception
E ChantlerM Elstein
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