PMID: 6329437May 28, 1984Paper

Release of endogenous dopamine from electrically stimulated slices of rat striatum

Brain Research
J D Milner, R J Wurtman

Abstract

An experimental system is described for measuring the release of endogenous dopamine from electrically stimulated slices of rat striatum. Striatal slices were field-stimulated by two high frequency trains (S1 and S2) applied 10, 30 or 60 min apart. The quantities of dopamine released by the two stimuli were compared from slices incubated with and without dopamine's precursor, L-tyrosine. Sustained release of dopamine evoked by the two stimuli was shown to require the inclusion of tyrosine (50 microM) in the superfusate.

References

Mar 14, 1977·Naunyn-Schmiedeberg's Archives of Pharmacology·K Dismukes, A H Mulder
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Citations

Jun 1, 1988·Cellular and Molecular Neurobiology·R J Baldessarini, M Vogt
Jan 1, 1986·Neurochemistry International·J M Pinto, T J Maher
Dec 1, 1989·Journal of Neurochemistry·J D Schaechter, R J Wurtman
Nov 13, 1992·Brain Research·C J Gibson
Apr 11, 2008·Brain Research·George E JaskiwRodolfo Bongiovanni
Nov 1, 1986·Journal of Neurochemistry·J D MilnerR J Wurtman
Mar 1, 1994·Annals of Biomedical Engineering·R J Tallarida, K A Freeman
Mar 15, 1986·Biochemical Pharmacology·J D Milner, R J Wurtman

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