PMID: 9541126Apr 16, 1998Paper

Release of peptide YY and inhibition of gastric acid secretion by long-chain and medium-chain triglycerides but not by sucrose polyester in men

European Journal of Clinical Investigation
M I MaasJ B Jansen

Abstract

In the present study, we have investigated the effects of intraduodenal perfusion of long-chain and medium-chain triglycerides and of sucrose polyester on the release of peptide YY in healthy men. Perfusion of medium-chain triglycerides (180 mmol fatty acids) increased the plasma concentration of peptide YY from 7.9 pmol L(-1) (SEM 0.2, n=8) to 10.7 pmol L(-1) (SEM 0.5, n=8), whereas perfusion of long-chain triglycerides (180 mmol fatty acids) had a significantly greater effect, increasing peptide YY concentration from 8 6 pmol L(-1) (SEM 0.2, n=8) to 18.9 pmol L(-1) (SEM 2.4, n=8, P < 0.008). A smaller quantity of long-chain triglycerides (90 mmol fatty acids) increased plasma concentration of peptide YY from 7.4 pmol L(-1) (SEM 0.4, n=8) to 13.3 pmol L(-1) (SEM 1.5, n=8), whereas sucrose polyester (90 mmol fatty acids) did not change peptide YY concentration. In a previous study, we investigated gastrin-stimulated gastric acid output in response to these treatments. The correlation between increases in peptide YY in response to all treatments and the decrease in acid output was r=0.72 (n=48, P < 0.0001). These results show that both long-chain and medium-chain triglycerides, but not sucrose polyester, stimulate the release of...Continue Reading

References

Aug 1, 1992·The American Journal of Physiology·K W RundellR L Terjung
May 1, 1991·The Journal of Surgical Research·B W KuvshinoffD W McFadden
Jul 1, 1991·Digestive Diseases and Sciences·T HashimotoJ C Thompson
Jan 1, 1990·Digestion·O Olsen, J Christiansen
Jul 1, 1990·The Journal of Endocrinology·D J O'HalloranS R Bloom
Jan 1, 1985·Gastroenterology·G M AndersonD J Cohen
Jan 1, 1989·Scandinavian Journal of Gastroenterology. Supplement·Y HashimotoY Saitoh
Apr 1, 1989·The Journal of Surgical Research·D W McFaddenJ E Fischer
Jan 1, 1986·The Journal of Clinical Investigation·T N PappasI L Taylor
Dec 1, 1988·Proceedings of the Society for Experimental Biology and Medicine·G H GreeleyJ C Thompson
Mar 1, 1989·Endocrinology·G H GreeleyJ C Thompson
Oct 1, 1987·The Journal of Clinical Investigation·M H MogardJ H Walsh
Sep 1, 1985·Gastroenterology·T E AdrianS R Bloom
Nov 1, 1985·Gastroenterology·T E AdrianS R Bloom
Feb 21, 1970·British Medical Journal·M A Hassan, M Hobsley
Oct 1, 1983·The Australian Journal of Experimental Biology and Medical Science·A ShulkesJ H Walsh
May 1, 1981·The American Journal of Physiology·R C Deth, C J Lynch
Feb 1, 1984·The Journal of Clinical Investigation·J H KleibeukerJ H Walsh
Apr 1, 1982·Digestive Diseases and Sciences·J B Jansen, C B Lamers
Feb 1, 1980·Digestive Diseases and Sciences·V MaxwellM I Grossman
Jul 1, 1980·The American Journal of Physiology·G A Ahearn
Jan 1, 1980·Immunological Communications·A PolsonM H van Regenmortel
Apr 1, 1996·Endocrinology·G GomezG H Greeley
Mar 1, 1997·The American Journal of Clinical Nutrition·M I MaasJ B Jansen

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Citations

Dec 15, 2000·European Journal of Clinical Investigation·F van HoekJ B Jansen
Nov 28, 2002·Journal of Pediatric Gastroenterology and Nutrition·Meenakoemarie Sharman-KoendjbiharieDick Tibboel
Feb 9, 2005·Journal of Pediatric Gastroenterology and Nutrition·M N HanekampD Tibboel
Nov 14, 2013·Seminars in Liver Disease·Jamie Eugene Mells, Frank A Anania
Aug 17, 2005·European Journal of Clinical Investigation·J Mössner, K Caca
Jan 27, 2006·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·E M R Kovacs, D J Mela
Oct 30, 2004·Scandinavian Journal of Gastroenterology·W P M HopmanJ B M J Jansen
Mar 17, 2000·Scandinavian Journal of Gastroenterology·F HoentjenJ B Jansen
Jul 31, 2014·European Journal of Clinical Nutrition·M-P St-OngeB Laferrère
Mar 7, 2002·The Journal of Nutrition·Marie-Pierre St-Onge, Peter J H Jones
May 26, 2004·The American Journal of Clinical Nutrition·Cees de GraafHenk F J Hendriks
Jan 24, 2018·Critical Reviews in Food Science and Nutrition·Tyler Maher, Miriam E Clegg
Aug 8, 1998·The American Journal of Physiology·M LedeboerC B Lamers
Jan 29, 2017·BMC Complementary and Alternative Medicine·Renuka GunasekaranNoraishah Mydin Abdul-Aziz
Oct 9, 2001·Scandinavian Journal of Gastroenterology·F HoentjenJ B Jansen

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