PMID: 6028400Jul 21, 1967Paper

Release of slow-reacting substance of anaphylaxis in the rat: polymorphonuclear leukocyte

Science
R P OrangeK F AUSTEN

Abstract

The antigen-induced release of slow-reacting substance of anaphylaxis was studied in rats previously treated with different biological and pharmacological agents to deplete these animals of specific cellular elements. The polymorphonuclear leukocyte appears necessary as a crucial cell type for optimum release of the slow-reacting substance of anaphylaxis, whereas the mast cell and lymphocyte are not required.

References

Feb 1, 1967·British Journal of Pharmacology and Chemotherapy·L M Greenbaum, K S Kim
Nov 1, 1959·Experimental Cell Research·B UVNAS, I L THON
Jan 1, 1955·The Anatomical Record·D W FAWCETT
Jan 1, 1967·British Journal of Pharmacology and Chemotherapy·Y Gabr, N Amin

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Citations

Sep 1, 1970·Arthritis and Rheumatism
Jan 1, 1969·European Journal of Pharmacology·W H FunderburkJ W Ward
Oct 1, 1968·The Journal of Experimental Medicine·N S Ranadive, C G Cochrane
Dec 1, 1991·Endodontics & Dental Traumatology·M TorabinejadG Lessard

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.