Relevance of testicular histopathology on prediction of sperm retrieval rates in case of non-obstructive and obstructive azoospermia

Urologia
G CitoA Natali

Abstract

The aim of our research was to establish the relevance of testicular histopathology on sperm retrieval after testicular sperm extraction in patients with non-obstructive azoospermia and in patients with obstructive azoospermia, who already underwent a previous failure testicular fine needle aspiration. We evaluated a total of 82 azoospermic men, underwent testicular sperm extraction, referring to the Assisted Reproductive Technology Centre of the University of Florence, Italy between January 2008 and March 2017. A general and genital physical examination, scrotal and trans-rectal ultrasound, semen analysis, hormone measurements, including follicle-stimulating hormone, luteinizing hormone and total testosterone, were collected. Successful sperm retrieval was obtained in 36 men of total (43.9%). Successful sperm retrieval was 29.5% in non-obstructive azoospermia patients, while men with obstructive azoospermia, who, underwent a previous failure testicular fine needle aspiration, had sperm retrieval in 86% of cases. Mean luteinizing hormone was 6.55 IU/L, total testosterone 4.70 ng/mL, right testicular volume 13.7 mL and left testicular volume 13.6 mL. Mean Follicle-stimulating hormone was 13.45 IU/L in patients with negative sper...Continue Reading

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Citations

May 17, 2019·The American Journal of Surgical Pathology·Hari P DhakalChristopher G Przybycin
Dec 13, 2018·Clinical and Experimental Reproductive Medicine·Gianmartin CitoAlessandro Natali
Apr 27, 2021·Systems Biology in Reproductive Medicine·Augusto B ReisHélio Chiarini-Garcia

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Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

SPSS
TESE

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