Relevant criteria for selecting an intravenous immunoglobulin preparation for clinical use

BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
Patrick Chérin, Jean Cabane

Abstract

Over the past several decades, the use of intravenous human normal immunoglobulin (IVIg) products in a diverse range of immunodeficiency, inflammatory and infectious disorders has increased significantly. Newer manufacturing processes have increased the yield of intact IVIg molecules and have also improved the tolerability and safety of these products, including reducing the transmission risk of blood-borne diseases. While there are no appreciable differences between the numerous commercially available IVIg products in terms of efficacy, different manufacturing processes and the final composition of IVIg products have resulted in different safety and tolerability profiles. The tolerability profile of different IVIg products may be idiosyncratic for individual patients and may not be predictable, based on product characteristics. Consequently, patients receiving an IVIg product should be carefully monitored at initial exposure, and switching of products should be avoided. To achieve the best outcomes in patients requiring IVIg therapy, treatment should be tailored to the patient's needs. The risk/benefit profile of an IVIg in relation to patient risk factors and the underlying immune deficiency, or autoimmune or inflammatory dis...Continue Reading

References

Jul 14, 1990·Lancet·S NimmannitS Nilwarangkur
Jun 1, 1995·The Journal of Pediatrics·E A RosenfeldC Kuroda
Jul 1, 1993·Journal of Clinical Immunology·C Cunningham-RundlesS Courter
Dec 30, 1993·The New England Journal of Medicine·M C DalakasS McCrosky
Sep 16, 1999·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·U E Nydegger, M Sturzenegger
Sep 8, 2001·The New England Journal of Medicine·M D Kazatchkine, S V Kaveri
Jul 19, 2003·Clinical and Experimental Immunology·V M BrennanUNKNOWN Immunology Nurses Study
Sep 23, 2003·The Hematology Journal : the Official Journal of the European Haematology Association·Milica ColovicAndrija Bogdanovic
Oct 23, 2003·Transfusion Medicine Reviews·L Ross Pierce, Nisha Jain
Mar 27, 2004·Thrombosis and Haemostasis·James B BusselUNKNOWN IGIV-C in ITP Study Group
Apr 29, 2004·Journal of Clinical Immunology·Hans D OchsUNKNOWN Octagam Study Group
Mar 26, 2005·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Sachin Shah, Marne Vervan
Jun 23, 2005·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Daphna ParanRonen Ben-Ami
Aug 16, 2005·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Mark Ballow
Aug 16, 2005·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Sachin Shah
Oct 19, 2005·Pharmacotherapy·Jerry Siegel
Nov 24, 2005·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Erwin W Gelfand
Dec 20, 2005·Vox Sanguinis·F G TerpstraF A C van Engelenburg
Dec 27, 2005·Best Practice & Research. Clinical Haematology·R John Looney, Jennifer Huggins
Jan 18, 2006·Journal of Neuroimmunology·Gang ZhangKazim A Sheikh
Jan 21, 2006·The Journal of Pediatrics·E Richard Stiehm
Jan 21, 2006·The Journal of Pediatrics·Ming-Han TsaiLuan-Yin Chang
Mar 1, 2006·International Immunopharmacology·Jerry Siegel
Mar 1, 2006·International Immunopharmacology·David J Hamrock
Apr 4, 2006·The Journal of Allergy and Clinical Immunology·Jordan S OrangeUNKNOWN Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology
May 18, 2006·Journal of Clinical Immunology·Joseph A ChurchUNKNOWN US-PID-IGIV 10% -Study Group10
Aug 2, 2006·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Jane Kirmse
Aug 2, 2006·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Brenda ReidNathalie Boissonneault
Oct 25, 2006·Autoimmunity·Uriel KatzAnat Achiron
Jul 20, 2007·Pharmacoepidemiology and Drug Safety·Anette DebesSybille Kremer
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Ashley A VoStanley C Jordan

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Citations

Jun 5, 2013·Expert Review of Clinical Immunology·Adam SunLeman Yel
Feb 26, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Siraj A Misbah
Sep 20, 2015·Autoimmunity Reviews·Patrick CherinJean-François Viallard
Jul 7, 2015·International Journal of Dermatology·Virendra N SehgalAnanta Khurana
Aug 17, 2011·International Immunopharmacology·Allison Baxley, Mojtaba Akhtari
Jun 24, 2017·Expert Review of Hematology·Dian WinkelhorstEnrico Lopriore
Sep 3, 2017·Wiener medizinische Wochenschrift·Lyubomir A DourmishevLjubka G Miteva
Oct 4, 2017·Pharmacology Research & Perspectives·Laia AlsinaUNKNOWN investigators of the Flebogamma DIF PASS Study Group
Jul 1, 2014·European Journal of Immunology·W A Carrock SewellHans-Hartmut Peter
Jul 29, 2016·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Stephen D BetschelRobert Schellenberg
Dec 2, 2017·Transfusion·Anna Gurevich-ShapiroPia Raanani
Sep 12, 2015·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·R Ts Bembeeva, N N Zavadenko

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