Reliability and validity of the Medication Adherence Rating Scale in a cohort of patients with schizophrenia from Nigeria

Trends in psychiatry and psychotherapy
Godspower O OwieBawo O James

Abstract

Assessing adherence in schizophrenia facilitates interventions that optimize outcomes. Adherence rating questionnaires are feasible and non-intrusive; however, no validated measure exists in sub-Saharan Africa. We aimed to assess the psychometric properties of the 10-item Medication Adherence Rating Scale (MARS). This was a cross-sectional study of a cohort of patients with schizophrenia (n=230). A sociodemographic questionnaire, the Mini International Neuropsychiatric Interview (MINI), Positive and Negative Syndrome Scale (PANSS), Scale for the Unawareness of Mental Disorder (SUMD) and the MARS were all administered by an interviewer. The MARS demonstrated good reliability (Cronbach's alpha: 0.76). The scale was reducible to a 3-factor construct (1 - medication adherence behavior, 2 - attitude to taking medications, and 3 - negative side effects and attitude to psychotropics), with significant though weak external validity in relation to psychopathology (p<0.001) and insight (p<0.001). The first factor showed good internal consistency (α=0.80), comprising six items that could serve as a reliable proxy measure of adherence in place of the MARS. The MARS demonstrated fair psychometric characteristics in assessing adherence in pa...Continue Reading

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Citations

Oct 9, 2020·Journal of Medical Internet Research·Yu Heng KwanJulian Thumboo
Oct 10, 2020·Journal of Medical Internet Research·Yu Heng KwanJulian Thumboo
Aug 20, 2021·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Md Ashraful IslamSunil Kripalani

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