Reliability of methods to estimate the fraction of inspired oxygen in patients with acute respiratory failure breathing through non-rebreather reservoir bag oxygen mask

Thorax
Rémi CoudroyArnaud W Thille

Abstract

Severity of hypoxaemia can be assessed using the partial pressure of arterial oxygen to fraction of inspired oxygen ratio (FiO2). However, in patients breathing through non-rebreather reservoir bag oxygen mask, accuracy of bedside FiO2 estimation methods remains to be tested. In a post-hoc analysis of a multicentre clinical trial, three FiO2 estimation methods were compared with FiO2 measured with a portable oxygen analyser introduced in the oxygen mask. Among 262 patients analysed, mean (SD) measured FiO2 was 65% (13). The 3%-formula (21% + oxygen flow rate in L/min × 3) was the most accurate method to estimate FiO2 Other methods overestimated FiO2 and hypoxaemia severity, so they should be avoided.

References

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Dec 3, 2009·JAMA : the Journal of the American Medical Association·Jean-Louis VincentUNKNOWN EPIC II Group of Investigators
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Citations

Dec 6, 2020·Current Opinion in Critical Care·Arnaud W ThilleJean-Pierre Frat
Dec 23, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Antonio PisanoGiovanni Landoni
Jun 30, 2021·Critical Care : the Official Journal of the Critical Care Forum·Arnaud W ThilleUNKNOWN HIGH-WEAN Study Group and the REVA research network
Nov 21, 2021·Scientific Reports·Carlos Fernando ValenciaPeter Alfonso Olejua

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