Reliability of the Laboratory Risk Indicator in Necrotising Fasciitis (LRINEC) score

The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
Muhammad AbdullahSaad U Khan

Abstract

The LRINEC score was introduced in 2004 but it has not yet been incorporated as a reliable diagnostic tool in the management of Necrotising Fasciitis. NF is uncommon and proportionately the evidence is limited, but the contradictory literature has resulted in varying individual concepts and clinical practices. This article is aimed to evaluate the reliability of the LRINEC score and determine its effectiveness based on the current available evidence. Eighteen clinical studies published during 2004-2018 were identified after an extended literature search and critically appraised to determine the validity, reliability and applicability of the individual pieces of evidence. The recommendations for practice were formulated after summative analysis of the evidence. The systemic review and observational studies report the LRINEC score has a variable range of sensitivity (43.2-80%), positive predictive value (57-64%) and negative predictive value (42-86%) which is lower than the initial results by Wong et al. (2004). The LRINEC score ≥6 correlates well with diagnosis of NF but 7.1 was found to be statistically significant. Higher LRINEC score correlates with higher SOFA score, prolonged ICU and hospital stay, and mortality. It is not ...Continue Reading

Citations

May 10, 2020·Clinical Orthopaedics and Related Research·Eleanor H Sato, Christopher M Domes
Feb 9, 2021·Diagnostic Microbiology and Infectious Disease·Pinar Sen, Tuna Demirdal
May 18, 2020·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Susumu AdachiKatsushi Takeshita
Jul 30, 2021·Journal of Burn Care & Research : Official Publication of the American Burn Association·Marc DanielsHarun Seyhan
Sep 18, 2021·World Journal of Emergency Surgery : WJES·Antonio TarasconiFausto Catena
Oct 7, 2021·The International Journal of Lower Extremity Wounds·Xiaojing GeXin Su

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