PMID: 7537867Jan 9, 1995Paper

REM sleep deprivation induces galanin gene expression in the rat brain

Neuroscience Letters
J ToppilaT Porkka-Heiskanen

Abstract

Rats were deprived of REM sleep for 24 h by keeping them on small platforms that were placed in a water bath (the platform method). Galanin coding mRNA was visualized using in situ hybridization, and cells expressing galanin mRNA were counted. In REM sleep-deprived animals the cell count was higher in the preoptic area and periventricular nucleus. Lesions of this area have been reported to induce wakefulness in cats and rats. Galanin administered into the lateral ventricle had no effect on sleep. We conclude that REM sleep deprivation can induce galanin gene expression in some brain areas, but galanin alone does not modify spontaneous sleep.

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Citations

Nov 20, 2003·Brain Research. Molecular Brain Research·Hiroaki FujiharaYusuke Morita
Jun 15, 1999·Journal of Psychiatric Research·H MurckA Steiger
Jun 18, 2003·Respiratory Physiology & Neurobiology·Miroslaw Mackiewicz, Allan I Pack
Jan 14, 2005·Proceedings of the National Academy of Sciences of the United States of America·Xiaoying LuTamas Bartfai
Dec 5, 2009·Critical Reviews in Food Science and Nutrition·Emily J McAllisterDavid B Allison
Aug 14, 2012·Respirology : Official Journal of the Asian Pacific Society of Respirology·Wei WangLin Wang
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Dec 5, 2000·Brain Research·C Cirelli, G Tononi
Dec 8, 2006·Expert Opinion on Therapeutic Targets·Seiji Nishino, Nobuhiro Fujiki
Jun 17, 2006·Journal of Psychiatric Research·Axel Steiger
Sep 1, 2006·Expert Review of Endocrinology & Metabolism·Axel Steiger
May 27, 1999·Annals of Medicine·C Cirelli, G Tononi
May 27, 1999·Annals of Medicine·J Toppila, T Porkka-Heiskanen
Jun 26, 2003·Journal of Internal Medicine·A Steiger
Aug 18, 2018·Neuroscience Research·Charlotte HéricéShuzo Sakata

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