Remaining controversies in the upfront management of advanced ovarian cancer

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
M S ManoM J Piccart

Abstract

Ovarian cancer (OC) is one of the leading causes of cancer-related death in women. In the last decades, a lot of energy and resources have been put into a number of clinical trials, with some success. Nevertheless, the prognosis of patients diagnosed with advanced disease remains extremely poor. As research moved forward, some crucial questions with regard to the optimal upfront management of patients with advanced OC (AOC) have remained unanswered. In this article, we review the rationale behind these controversial issues, and provide the levels of evidence supporting the current recommendations for AOC management.

References

Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J P NeijtM van Lent
Apr 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G A OmuraR Mortel
Dec 1, 1982·Annals of Internal Medicine·S B HowellM Green
Jul 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W P McGuireJ Woodward
Dec 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·E A EisenhauerN Colombo
May 1, 1993·Annals of Oncology : Official Journal of the European Society for Medical Oncology·D MurphyV R Tindall
Nov 3, 1993·Journal of the National Cancer Institute·L LevinW Hryniuk
Feb 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P F ConteA Rubagotti
Jul 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S B KayeR P Symonds
Jan 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D FennellyD Spriggs
Jan 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A JakobsenI Stroeyer
Apr 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P J StiffS G Fisher
Apr 1, 1997·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H E LambertA E Nelstrop
May 20, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C AghajanianD R Spriggs
Jul 17, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M GoreJ Shepherd
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C MarthG B Kristensen
Nov 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R J SchilderR F Ozols
Jan 7, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F M MuggiaJ M Small
Aug 30, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J P NeijtH C van Houwelingen
Jan 9, 2001·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·M S YenC C Yuan
Jul 4, 2001·Annals of Oncology : Official Journal of the European Society for Medical Oncology·J A LedermannG Rosti
Aug 8, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·H J LückUNKNOWN AGO-GINECO Intergroup
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Don S DizonDavid R Spriggs
May 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Maurie MarkmanMark Baker
Jun 12, 2002·Current Treatment Options in Oncology·M E van der Burg
Oct 10, 2002·British Journal of Cancer·J SandercockW Qian
Dec 31, 2002·Critical Reviews in Oncology/hematology·Hilary Thomas, Per Rosenberg

❮ Previous
Next ❯

Citations

Feb 13, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A A GarsaA Wu
Feb 13, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A GadducciE Sartori
Aug 30, 2008·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A GadducciA R Genazzani
Feb 27, 2008·World Journal of Gastroenterology : WJG·Hassan-Alaa-Hammed Al-ShammaaYutaka Yonemura
Feb 22, 2005·Gynecologic Oncology·Bradley J MonkRobert A Burger
Sep 1, 2009·Gynecologic Oncology·Talia FosterThomas J Herzog
Sep 10, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Hiroaki KajiyamaFumitaka Kikkawa
Mar 1, 2006·Expert Review of Anticancer Therapy·M Faruk KoseGökhan Tulunay
Mar 1, 2007·Expert Review of Endocrinology & Metabolism·Angiolo GadducciAndrea Riccardo Genazzani

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved