Remapping of place cell firing patterns after maze rotations

Experimental Brain Research
Arnaud CressantB Poucet

Abstract

When place cells are recorded from rats running on an elevated T-maze inside a curtained enclosure that contains distinct, experimenter selected stimuli, rotations of the maze plus stimuli cause equal rotations of firing fields. Here, we examined the effects of conflicting rotations of a T-maze relative to a laboratory frame that contained a large number of fixed stimuli in the environment and asked whether positional firing patterns stayed in register with the maze or the room cues or were modified in some more complex way. After maze rotations of 90 degrees, 180 degrees or 270 degrees, firing fields were stable in the laboratory frame and thus shifted to a different maze arm. In contrast, rotations of 45 degrees or -45 degrees resulted in dramatic changes of positional firing patterns regardless of their initial position on the maze. Crucially, even cells whose fields were initially on the central platform underwent major firing pattern alterations although the view of the environment from the platform was unchanged by such rotations. Finally, we found that altering the visual appearance by removing without rotation one or two maze arms did not alter firing fields on the remaining part of the maze. Thus, the "remappings" caus...Continue Reading

Citations

Feb 22, 2002·Journal of Cellular Physiology·Lisa Macera-BlochHarvey L Ozer
Feb 24, 2007·Animal Cognition·Osnat Yaski, David Eilam
Nov 14, 2003·Brain Research. Brain Research Protocols·Arnaud Cressant, Sylvie Granon
Dec 16, 2004·Behavioral Neuroscience·Philip BarnesMark Good
Jan 20, 2006·Behavioral Neuroscience·Paul A Dudchenko, Larissa E Zinyuk
Sep 3, 2004·The European Journal of Neuroscience·V Paz-VillagránB Poucet
Aug 2, 2008·The European Journal of Neuroscience·Jonathan A OlerEtan J Markus
Mar 21, 2007·Hippocampus·Sophie RenaudineauEtienne Save
Sep 3, 2013·Hippocampus·Thomas GenerMaria V Sanchez-Vives
Sep 20, 2019·Reviews in the Neurosciences·Roger D TraubJames I Nagy
Feb 2, 2021·Frontiers in Behavioral Neuroscience·Omid MiryLu Chen
Sep 23, 2020·Current Biology : CB·Ryan A WirtJames M Hyman

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