Remineralisation of enamel white spot lesions pre-treated with chitosan in the presence of salivary pellicle

Journal of Dentistry
Jing ZhangA Banerjee

Abstract

To investigate the remineralisation of chitosan pre-treated enamel white spot lesions (WSLs) by bioglass in the presence of the pellicle layer. 50 artificial enamel white spot lesions were created by acidic gel. Two lesions were used to investigate the formation of the pellicle layer by treating with human whole saliva for 3 min. 48 lesions were assigned to 6 experimental groups (n = 8): (1) bioactive glass slurry, (2) bioactive glass containing polyacrylic acid (BG + PAA) slurry, (3) chitosan pre-treated WSLs with BG slurry (CS-BG), (4) chitosan pre-treated WSLs with BG + PAA slurry (CS-BG + PAA), (5) "standard" remineralisation solution (RS) and (6) de-ionised water (negative control, NC). Remineralisation was carried out using a pH-cycling model for 7 days. Before each treatment using remineralising agents, 3-min pellicle was formed on lesions' surfaces. Mineral content changes, surface and subsurface microhardness and ultrastructure were evaluated by Raman intensity mapping, Knoop microhardness and scanning electron microscopy, respectively. Data were statistically analysed using one-way ANOVA with Tukey's test (p < 0.05 is considered as significant). Despite the heterogeneously formed pellicle layer, all groups showed an i...Continue Reading

Citations

Oct 18, 2018·Journal of Dental Research·L S GuL N Niu
Nov 20, 2019·Journal of Dentistry·Núbia Inocencya Pavesi PiniNadine Schlueter
Sep 10, 2021·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Luisa Alegria AcevedoFabio André Santos
Jul 2, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Caroline MocquotPierre Colon

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