Remineralization of in vitro dental caries assessed with polarization-sensitive optical coherence tomography

Journal of Biomedical Optics
Robert S JonesD Fried

Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) is potentially useful for imaging the nonsurgical remineralization of dental enamel. This study uses an all-fiber-based PS-OCT system operating at 1310 nm to image demineralized and fluoride-enhanced remineralized artificial lesions. PS-OCT images of lesions before and after remineralization are compared with the relative mineral loss DeltaZ (%vol x microm), obtained from high resolution digital microradiography (DM), and chemical composition changes by infrared spectroscopy. Severe early artificial caries show a significant increase in perpendicular-axis integrated reflectivity after remineralization. After sectioning the samples, DM demonstrates that the lesions remineralized with new mineral and the lesion surface zone show significant restoration of mineral volume. PS-OCT and DM both do not show a major change in lesion depth. For less severe artificial caries, the perpendicular-axis image resolves the scattering and depolarization of an outer growth layer after remineralization. This outer layer has a mineral volume close to that of sound enamel, and spectroscopic analysis indicates that the layer is a highly crystalline phase of apatite, without carbonate substi...Continue Reading

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Citations

Aug 26, 2006·Journal of Dental Research·R S Jones, D Fried
Jul 17, 2013·Sensors·Yao-Sheng HsiehChia-Wei Sun
Nov 22, 2008·Journal of Biomedical Optics·Krista HirasunaCynthia L Darling
Nov 22, 2008·Journal of Biomedical Optics·Cosmin SinescuAdrian Gh Podoleanu
Aug 31, 2010·Journal of Biomedical Optics·Joey EnfieldMartin Leahy
Dec 30, 2011·Dental Materials : Official Publication of the Academy of Dental Materials·Hobin KangDaniel Fried
Mar 10, 2016·Lasers in Surgery and Medicine·Kenneth H ChanDaniel Fried
Jun 14, 2012·Lasers in Surgery and Medicine·Steven DuongPetra Wilder-Smith
Jun 22, 2010·Oral Diseases·P Wilder-SmithA Le
Sep 18, 2010·Lasers in Surgery and Medicine·Jennifer S HoltzmanPetra Wilder-Smith
Jun 5, 2013·Australian Dental Journal·H TasseryP Rechmann
Jan 16, 2010·Lasers in Surgery and Medicine·Michael H LeDaniel Fried
Jun 11, 2011·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Hobin KangDaniel Fried
Mar 5, 2015·Dental Materials : Official Publication of the Academy of Dental Materials·Hussam MillyAvijit Banerjee
Jun 27, 2013·The EPMA Journal·Anatoly A KuninDmitry A Kunin
Sep 20, 2016·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Robert C LeeDaniel Fried
Jun 16, 2015·Optics Express·Lian DuanAudrey K Ellerbee
May 5, 2018·Lasers in Medical Science·Kyung-Jin ParkRainer Haak

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