Remineralization potential of nano-hydroxyapatite on enamel and cementum surrounding margin of computer-aided design and computer-aided manufacturing ceramic restoration

International Journal of Nanomedicine
Niwut JuntaveePreeyarat Plongniras

Abstract

This study investigates the effects of nano-hydroxyapatite (NHA) gel and Clinpro (CP) on remineralization potential of enamel and cementum at the cavosurface area of computer-aided design and computer-aided manufacturing ceramic restoration. Thirty extracted human mandibular third molars were sectioned at 1 mm above and below the cemento-enamel junction to remove the cemento-enamel junction portions and replaced them with zirconia ceramic disks by bonding them to the crown and root portions with resin cement. The enamel and cementum with an area of 4×4 mm2 surrounding the ceramic disk was demineralized with carbopol. The demineralized surfaces were treated with either NHA or CP, while 1 group was left with no treatment. Vickers microhardness of enamel and cementum were determined before demineralization, after demineralization, and after remineralization. Analysis of variance and Tukey multiple comparisons were used to determine statistically significant differences at 95% level of confidence. Scanning electron microscopy and X-ray diffraction were used to evaluate for surface alterations. The mean ± SD of Vickers microhardness for before demineralization, after demineralization, and after remineralization for enamel and cement...Continue Reading

Citations

Jan 16, 2020·Foundations of Science·Victoria Wu, Vuk Uskoković
May 13, 2020·Drug Metabolism Reviews·Ioana Roxana BordeaDoina Adina Todea
Jul 30, 2021·Clinical, Cosmetic and Investigational Dentistry·Bennett Tochukwu AmaechiJoachim Enax

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