Remission in diabetic children in Riyadh

Annals of Saudi Medicine
H Salman

Abstract

Few data are available about temporary remission in insulin dependent mellitus in Riyadh. Thirty-seven out of 115 (32.1%) diabetic children diagnosed over five and a half years (1985 to mid-1990) in Suleimania Children's Hospital were retrospectively studied. Partial temporary remission rate was 30.4% (35/115). Total temporary remission rate was 1.7% (2/115), lasting 18 months in a seven-year-old patient. The partial remission rate was higher in children above five years of age (36.9%), in children of unrelated parents (34.3%) and in female patients (51.4%). Of these, 64.8% were Saudi. Fifty-four percent of these patients presentd at onset without diabetic ketoacidosis and mean duration of symptoms before diagnosis was short (9.2 days). Mean time of occurrence was five weeks and mean duration of remission was nine weeks. Mean initial insulin dose was 1.35 unit/kg/day, while mean dose during the remission was 0.34 unit/kg/day. Mean glycosylated hemoglobin at onset was 12.3% and 7.4% during remission. Mean C-peptide level improved markedly from 0.16 nmol/L at onset to 0.29 nmol/L during remission and rose to 0.61 nmol/L following glucagon intravenous injection demonstrating the temporary recovery of pancreatic B-cell function. Fi...Continue Reading

References

Dec 1, 1985·Archives of Disease in Childhood·I G JeffersonJ D Baum
Nov 30, 1968·Lancet·R Illig, A Prader

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Related Papers

Diabetic Medicine : a Journal of the British Diabetic Association
H SalmanM Khalil
Indian Journal of Pediatrics
G JainB M Shah
Indian Journal of Pediatrics
Anju SethV Taluja
© 2021 Meta ULC. All rights reserved