Remission in psoriatic arthritis: Definition and predictors.

Seminars in Arthritis and Rheumatism
Samar AlharbiDafna D Gladman

Abstract

To determine the frequency of remission defined by the absence of the various disease manifestations of psoriatic arthritis (PsA) and identify predictors for remission. Patients followed at the PsA clinic between 2000 and 2015 were included. Patients are assessed at 6- to 12-month intervals according to a standard protocol. Remission was defined as a visit that patients had no tender or swollen joints, no inflammatory back pain, no tender entheseal sites, minimal skin involvement with BSA<1%, patient pain on visual analog scale (VAS) score of <15, patient global disease activity VAS score of <20, Health Assessment Questionnaire (HAQ) score <0.5. We used imputation approach to determine remission status for visits with incomplete criteria for each patient. Data from 985 patients (57% males, average age of 47.4 years) were included in this study. From 2000 to 2015, 175 (18%) patients achieved remission at least once and 92 (9%) experienced sustained remission over at least 2 consecutive visits. In a multivariate Weibull regression analysis for the time to remission, higher BMI was associated with lower chance of remission (HR = 0.96, p = 0.012), while the use of biologics increased the chance of achieving remission (HR = 1.48, p ...Continue Reading

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Citations

Nov 4, 2020·The Journal of Rheumatology·Ana-Maria Orbai
Feb 18, 2021·RMD Open·Roberta RamondaUNKNOWN on behalf Spondyloartritis and Psoriatic Arthritis SIR Study Group “Antonio Spadaro”

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