PMID: 9661806Jul 14, 1998Paper

Remission of hypertension: retrospective observations over a period of 20 years

Hypertension Research : Official Journal of the Japanese Society of Hypertension
T SugiyamaJ Fujii

Abstract

To clarify the background and outcome of hypertensive patients who have remission of their elevated blood pressure (BP) after a course of antihypertensive drug therapy, we designed a retrospective observational study. The clinical records of 106 hypertensive men and women (BP, 164.3/104.4 mmHg) given antihypertensive drug treatment and subsequently examined every 1 to 3 mo for more than 20 yr were reviewed. The patients were divided into two groups: those who had remission (R-group) and those who did not have remission (N-group). Patients were considered in remission if no significant elevation in BP was observed for more than 1 yr after withdrawing their medication. Remissions ranging in duration from 1.6 to 21.7 yr (average duration, 6.3 yr) occurred in 19 of 106 patients (17.9%). However, anti-hypertensive drug treatment was eventually restarted in 17 of the 19 patients. Before treatment, comparison of the R-group and N-group revealed no differences with respect to age, body weight, BP, or serum creatinine. In contrast, the proportion of patients who lacked high-voltage deflections in their electrocardiograms (ECG) as well as that of patients whose BP was well-controlled by a single medication was significantly greater in th...Continue Reading

Citations

Mar 28, 2013·Clinical and Experimental Hypertension : CHE·Kanako KiyoharaKiyoshi Matsumura
Jan 1, 2017·Methods of Information in Medicine·Adel AlaeddiniMary J Pugh
Aug 4, 2019·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Satoshi UmemuraNobuhito Hirawa

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