PMID: 9428139Jan 1, 1997Paper

Remnants of Albunex nucleate acoustic cavitation

Ultrasound in Medicine & Biology
D DaleckiE L Carstensen

Abstract

Mice were injected with 0.1 mL Albunex and exposed to 200 pulses from a piezoelectric lithotripter at times ranging from 5 min to 24 h following injection. Each pulse was approximately 1.5 sinusoidal oscillations at a fundamental frequency of approximately 0.1 MHz with pressure amplitude of approximately 2 MPa. Although the contrast agent ceases to be an effective scatterer of diagnostic ultrasound after a few minutes in the circulation, the modest lithotripter exposures caused significant hemorrhaging in bladder, mesentery and intestine for periods of up to 4 h after injection. The results demonstrate either that highly stable bubbles much smaller than resonance size or air-containing fragments of the shells of Albunex serve as effective nuclei for acoustic cavitation.

References

Jan 1, 1997·Ultrasound in Medicine & Biology·D DaleckiE L Carstensen
Jan 1, 1997·Ultrasound in Medicine & Biology·D DaleckiE L Carstensen
Feb 15, 2001·Echocardiography·C. H. RaemanE. L. Carstensen

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Citations

Jan 22, 2005·European Radiology·Jarl A JakobsenUNKNOWN Members of Contrast Media Safety Committee of European Society of Urogenital Radiology (ESUR)
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Dec 20, 2000·Ultrasound in Medicine & Biology·M W MillerA A Brayman
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Aug 24, 2000·Proceedings of the National Academy of Sciences of the United States of America·D L Miller, J Quddus
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Nov 12, 2003·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Binh C TranCharles A Cain
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Apr 15, 2016·World Journal of Gastroenterology : WJG·Natsuko Kawada, Sachiko Tanaka

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