Remote functionalization of the steroid side-chain

Lipids
E J ParishT L Boos

Abstract

By using classical methods of organic synthesis, the introduction of chemical modifications into the saturated side-chains of steroids usually requires a multistep synthesis to construct new side-chains to be added to the steroid nucleus. In order to circumvent these earlier methods, new procedures have been developed to directly introduce functionality onto the steroid side-chain to produce useful products. These initial products may also provide an entry toward the further modification of the side-chain to produce steroids which could previously be obtained only with great difficulty.

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Citations

Jan 5, 2002·Journal of Chromatography. a·P Volin
Nov 3, 2004·Chemistry : a European Journal·Bruno SchöneckerMartin Bohl
Mar 26, 2011·Bioorganic & Medicinal Chemistry Letters·Manmeet KumarRakesh Maurya

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