Remote magnetic actuation using a clinical scale system

PloS One
Jurgen RahmerBernhard Gleich

Abstract

Remote magnetic manipulation is a powerful technique for controlling devices inside the human body. It enables actuation and locomotion of tethered and untethered objects without the need for a local power supply. In clinical applications, it is used for active steering of catheters in medical interventions such as cardiac ablation for arrhythmia treatment and for steering of camera pills in the gastro-intestinal tract for diagnostic video acquisition. For these applications, specialized clinical-scale field applicators have been developed, which are rather limited in terms of field strength and flexibility of field application. For a general-purpose field applicator, flexible field generation is required at high field strengths as well as high field gradients to enable the generation of both torques and forces on magnetic devices. To date, this requirement has only been met by small-scale experimental systems. We have built a highly versatile clinical-scale field applicator that enables the generation of strong magnetic fields as well as strong field gradients over a large workspace. We demonstrate the capabilities of this coil-based system by remote steering of magnetic drills through gel and tissue samples with high torques ...Continue Reading

References

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Citations

Jan 10, 2020·Therapeutic Delivery·Himanshu GandhiDeepak N Kapoor
Apr 28, 2019·Nature Communications·M GraeserT Knopp
Sep 23, 2020·Micromachines·Elizabeth E NiedertDavid J Cappelleri
Jan 12, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Yao LuSteven Conolly
Jan 21, 2021·International Journal of Nanomedicine·Franz WegnerThomas Friedrich
May 29, 2021·Chemical Society Reviews·Chang LuJianghong Rao
Jun 11, 2021·Scientific Reports·Sangyeun ParkHongyun So
Sep 2, 2020·ACS Nano·Azaam AzizOliver G Schmidt
Oct 8, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Peter LudewigTobias Knopp

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Methods Mentioned

BETA
X-ray
biopsy

Software Mentioned

MPI

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