Removable interpenetrating network enables highly-responsive 2-D photonic crystal hydrogel sensors

The Analyst
Andrew E CoukoumaSanford A Asher

Abstract

Responsive hydrogels functionalized with molecular recognition agents can undergo large volume changes upon interactions with specific chemical species. These responsive hydrogels can function as chemical sensing materials if the hydrogel volumes are monitored by using devices such as photonic crystals (PhC). An important criterion of merit is the responsiveness of these sensing hydrogels. Generally, hydrogel responsiveness is inversely proportional to the hydrogel crosslink density because the elastic constants scale with the crosslink density. The responsivities of these hydrogel sensors dramatically increase as their hydrogel crosslinker concentrations decrease. Unfortunately, the resulting highly responsive hydrogels become fragile at low crosslink densities, and are hard to fabricate and utilize. To temporarily increase the mechanical strengths of these highly responsive hydrogels we developed a method to incorporate a removable reinforcing interpenetrating hydrogel network. We demonstrate the utility of this approach by incorporating an interpenetrating PVA hydrogel within a weak, low crosslinked pH sensitive hydrogel through a freeze-thaw process. These interpenetrating PVA hydrogels are indefinitely stable at room tempe...Continue Reading

References

Sep 1, 1996·Biomaterials·K S AnsethL Brannon-Peppas
Jan 5, 2002·Advanced Drug Delivery Reviews·Byeongmoon JeongYou Han Bae
Aug 20, 2002·Analytical and Bioanalytical Chemistry·Sanford A AsherDavid Finegold
Apr 23, 2003·Analytical Chemistry·Sanford A AsherMichelle M Ward
Nov 25, 2003·Analytical Chemistry·Alexander J MarshallChristopher R Lowe
Mar 5, 2004·Journal of the American Chemical Society·Anjal C SharmaSanford A Asher
Oct 1, 2004·Analytical Chemistry·Mei-Ching LeeChristopher R Lowe
Jul 28, 2005·Journal of the American Chemical Society·Alexander V Goponenko, Sanford A Asher
Nov 18, 2005·Journal of Colloid and Interface Science·Chad E Reese, Sanford A Asher
Nov 9, 2006·Nano Letters·Sung Yeun ChoiGeoffrey A Ozin
Oct 24, 2007·Nature Materials·Youngjong KangEdwin L Thomas
May 15, 2009·Analytical Chemistry·Michelle M Ward MuscatelloSanford A Asher
Dec 8, 2009·Chemistry of Materials : a Publication of the American Chemical Society·Sanford A AsherJeremy P Walker
Sep 4, 2010·Advanced Materials·Jun Young ChungChristopher M Stafford
May 25, 2011·Journal of the American Chemical Society·Jian-Tao ZhangSanford A Asher
May 9, 2012·Angewandte Chemie·Jian-Tao ZhangSanford A Asher
Jun 23, 2012·Analytical Chemistry·Jian-Tao ZhangSanford A Asher
Jun 8, 2013·Chemical Communications : Chem Comm·Jian-Tao ZhangSanford A Asher
Apr 29, 2014·Analytical Chemistry·Zhongyu CaiSanford A Asher
Aug 28, 2014·Analytical Chemistry·Jian-Tao ZhangSanford A Asher
Oct 24, 2014·The Analyst·Natasha L SmithSanford A Asher
Apr 14, 2015·Analytical Chemistry·Zhongyu CaiSanford A Asher
Jan 25, 2008·Sensors·Andreas RichterHans-Jürgen P Adler

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Chemistry of Materials : a Publication of the American Chemical Society
Sanford A AsherJeremy P Walker
Journal of the American Chemical Society
Jian-Tao ZhangSanford A Asher
© 2021 Meta ULC. All rights reserved