Removal of immunosuppressive substance in cancer patients' serum

Japanese Journal of Cancer Research : Gann
O IshikoT Sugawa

Abstract

Anemia-inducing substance (AIS) appears in plasma as cancer progresses. In this study, a non-coated charcoal column was used to remove AIS from the cachectic plasma obtained from patients with advanced cancer. AIS could be completely removed by 6 cycles of adsorption using this column. Similar data were obtained in an experiment using VX-2-transplanted rabbits. These observations raised the possibility that plasmapheresis with a non-coated charcoal column may be available as a new means of immunotherapy for advanced cancer.

Citations

Feb 15, 2001·Japanese Journal of Cancer Research : Gann·O IshikoS Ogita
Jun 29, 2001·Japanese Journal of Cancer Research : Gann·H YoshidaS Ogita
Jun 16, 1999·Nutrition and Cancer·O IshikoS Ogita
Aug 1, 1998·Japanese Journal of Cancer Research : Gann·S NakataS Ogita

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