Removal of two halves restores the whole: reversal of visual hemineglect during bilateral cortical or collicular inactivation in the cat

Visual Neuroscience
S G Lomber, B R Payne

Abstract

The purpose of the present study was to compare visual orienting behavior in the adult cat during (1) unilateral and bilateral cooling deactivation of posterior-middle suprasylvian (pMS) sulcal cortex, and (2) unilateral and bilateral deactivation of the superior colliculus. As expected, unilateral cooling deactivation of either pMS cortex or the superior colliculus resulted in a profound visual neglect of the contracooled hemifield. The addition of cooling the homotopic region in the opposite hemisphere largely reversed this deficit and restored visual orienting into the previously neglected hemifield. These results show that (1) pMS cortex and the superior colliculus are essential for normal detection and orienting to visual targets, and (2) unilateral visual neglect results from an imbalance of activities in the two hemispheres induced at either cortical or subcortical levels. These conclusions have implications for understanding neural bases of visual hemineglect following unilateral lesions in humans.

References

Oct 15, 1992·The Journal of Comparative Neurology·J K HartingD P Van Lieshout
Jan 1, 1991·International Journal of Law and Psychiatry·J Becker, R M Stein
Mar 1, 1991·Visual Neuroscience·B R PayneS G Lomber
Dec 22, 1988·The Journal of Comparative Neurology·J K HartingD P Van Lieshout
Jan 1, 1985·Experimental Brain Research·J P Joseph, D Boussaoud
Jan 14, 1972·Brain Research·M Bénita, H Condé
Dec 1, 1974·The Journal of Comparative Neurology·T Kanaseki, J M Sprague
Nov 1, 1972·Investigative Radiology·M S McLachlanA W Asscher
Sep 1, 1970·Canadian Journal of Physiology and Pharmacology·H H JasperJ Montplaisir
Jan 1, 1970·Brain, Behavior and Evolution·J M SpragueA Di Berardino
Oct 10, 1984·The Journal of Comparative Neurology·L L Symonds, A C Rosenquist
Dec 1, 1984·Journal of Neurophysiology·K OgasawaraB E Stein
May 10, 1984·The Journal of Comparative Neurology·R L Segal, R M Beckstead
Mar 1, 1980·The Journal of Physiology·L R Harris
Oct 1, 1981·Annals of Neurology·M M Mesulam
Apr 1, 1994·Current Opinion in Neurobiology·R D Rafal
May 1, 1994·Cerebral Cortex·T Pasternak, W H Merigan
Apr 12, 1994·Proceedings of the National Academy of Sciences of the United States of America·S G LomberB R Payne
Jan 9, 1996·Proceedings of the National Academy of Sciences of the United States of America·B R PayneE Vandenbussche
Feb 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·S G LomberP Cornwell
Jan 1, 1953·Proceedings of the Royal Society of Medicine·M CRITCHLEY
Jan 1, 1953·Giornale di psichiatria e di neuropatologia·M CRITCHLEEY
Jan 1, 1965·Experimental Neurology·J M SPRAGUE, T H MEIKLE

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Citations

Feb 26, 2004·Neuroscience·L R BurnettM T Wallace
Oct 21, 2000·Progress in Neurobiology·G Kerkhoff
Feb 7, 2001·Current Opinion in Neurobiology·A Pouget, J Driver
May 9, 2012·Proceedings of the National Academy of Sciences of the United States of America·Melanie WilkeRichard A Andersen
Mar 7, 2000·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·M P YoungJ W Scannell
Apr 5, 2011·Annual Review of Neuroscience·Neeraj J Gandhi, Husam A Katnani
Feb 29, 2008·Journal of Neurophysiology·Mark M G WaltonNeeraj J Gandhi
Jul 8, 1997·Proceedings of the National Academy of Sciences of the United States of America·W VanduffelG A Orban
Mar 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Stephen G Lomber
Sep 4, 2012·Biological cybernetics·Thomas BrandtStefan Glasauer
May 13, 2010·Experimental Brain Research·R J RushmoreAntoni Valero-Cabre
Oct 15, 2011·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Dario CazzoliThomas Nyffeler
Mar 1, 2005·The European Journal of Neuroscience·Anastasia ChristakouBarry J Everitt
Jul 22, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A SchröderV Hömberg
Apr 11, 2007·The European Journal of Neuroscience·Elizabeth J WilkinsonHelen Sherk
Jul 11, 2006·Neurobiology of Disease·Xiao-Feng YangSteven M Rothman
Jun 26, 2013·Hearing Research·Andres Carrasco, Stephen G Lomber
Oct 10, 2012·Neuropsychologia·José P OssandónPeter König
Feb 18, 2015·Frontiers in Neuroinformatics·S Katharina SchmitzRalf A W Galuske
Mar 4, 2015·Brain Stimulation·Giuseppe GigliaFilippo Brighina
Mar 23, 2012·Topics in Stroke Rehabilitation·Tatiana OgourtsovaAlain Ptito
Jun 29, 2016·BMC Neuroscience·Melissa ZavagliaClaus C Hilgetag
Apr 17, 2003·Experimental Brain Research·Bertram R PayneAlvaro Pascual-Leone
Feb 27, 2016·PloS One·Vincenzo De CiccoDiego Manzoni
Dec 18, 2003·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Bertram R Payne, R Jarrett Rushmore
Apr 17, 2002·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Bertram R Payne, Stephen G Lomber
Oct 4, 2014·Neuron·Sylvia Schröder, Matteo Carandini
Dec 31, 1997·The Journal of Comparative Neurology·V M CiaramitaroA C Rosenquist

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