Abstract
The objective was to evaluate the impact of urinary albumin excretion rate (UAER), glomerular filtration rate (GFR) and subclinical autonomic neuropathy (SANP) on 9-year total (TM) and sudden cardiac mortality (SCM) in recently diagnosed (< 1 year; RD; n = 150) and known (mean duration 11 years; KD; n = 146) NIDDM subjects. The study was prospective and controlled (n = 150). Mortality predictors were analysed by logistic regression analysis. The dependent variables were TM and SCM, the predictors were UAER, GFR, SANP, age, gender, BMI, mean arterial pressure (MAP), fasting serum cholesterol, HDL-cholesterol, triglycerides, insulin, haemoglobin A1c, diabetes duration, QTc-interval (ECG), coronary heart disease (CHD), peripheral vascular disease (PVD), cerebrovascular disease (CVD), congestive heart failure (CHF), antihypertensive therapy, and smoking habits. CHD predicted TM and SCM in both RD (P = 0.041 and 0.029) and KD (P = 0.034 and 0.006). PVD predicted TM and SCM in KD only (P = 0.001 and 0.003). CVD predicted TM and SCM in RD only (P = 0.001 and 0.017). In RD male gender (P = 0.049), fasting serum cholesterol (P = 0.007) and CHF (P = 0.001) predicted TM and in kDa haemoglobin A1c (P = 0.004), age (P = 0.001) and MAP (P = ...Continue Reading
Citations
Feb 22, 2003·Journal of Biomedical Science·Saara LehtinenTerho Lehtimäki
Jun 27, 2007·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Matthias Weck
May 11, 2004·Current Diabetes Reports·Fadi A El-AtatJ Thomas Bigger
Nov 2, 2001·Atherosclerosis·A G BostomJ Selhub
Sep 4, 1999·Clinical and Experimental Pharmacology & Physiology·S P McDonaldW E Hoy
May 6, 1999·Diabetic Medicine : a Journal of the British Diabetic Association·Y GroeneveldM P Springer
Jan 25, 2002·Postȩpy higieny i medycyny doświadczalnej·A Piwowar, M Warwas
Aug 21, 2013·BMC Nephrology·Zaimin WangZhiqiang Wang
Jul 14, 2010·European Journal of Medical Research·C MeyerT Rassaf
Aug 30, 2005·Radiology·Alison D MurrayLawrence J Whalley
Oct 29, 2010·International Journal of Cardiology·Tienush RassafChristian Meyer
Jul 1, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Zaimin WangKevan R Polkinghorne
Dec 3, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·S H KoY B Ahn
Dec 22, 2010·European Journal of Medical Research·T RassafChristian Meyer
May 27, 2003·Diabetes Care·Raelene E MaserRoy Freeman
Apr 14, 2012·Diabetes·Ulrik Madvig MogensenKlaus Fuglsang Kofoed
Oct 29, 2002·Diabetes Care·Allon N FriedmanUNKNOWN Collaborative Study Group
Jul 1, 2009·Diabetes Care·Hanneke J B H BeijersCoen D A Stehouwer
Feb 13, 2009·Renal Failure·Helen A TzanatosEirini Grapsa
Apr 9, 2016·Medicine·Bedile Irem TiftikciogluYasar Zorlu
Aug 10, 2001·Current Opinion in Nephrology and Hypertension·L D Dworkin
May 8, 2004·Journal of Endocrinological Investigation·M VeglioP Cavallo-Perin
May 10, 2005·QJM : Monthly Journal of the Association of Physicians·V BaskarB M Singh
Jan 10, 2021·BMC Nephrology·Noppawit AiumtrakulBancha Satirapoj
Jun 30, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A G Bostom, L D Dworkin