Renal Angina Is a Sensitive, but Nonspecific Identifier of Postcardiac Surgery Acute Kidney Injury.

Journal of Cardiothoracic and Vascular Anesthesia
Michael A FierroDuke Critical Care Outcomes Research Endeavors (C-CORE) Group

Abstract

Acute kidney injury (AKI) is a common complication of cardiac surgery, and early detection is difficult. This study was performed to determine the sensitivity, specificity, positive predictive value, negative predictive value, and statistical performance of renal angina (RA) as an early predictor of AKI in an adult cardiac surgical patient population. Retrospective, nonrandomized, observational study. A single, university-affiliated, quaternary medical center. The study comprised 324 consecutive patients undergoing coronary artery bypass grafting or cardiac valvular surgery from February 1 through July 30, 2014. None. One hundred-seven patients at moderate or high risk of developing postoperative renal injury were identified, 82 of whom met criteria for RA. The occurrence of RA was found to have an 80.9% sensitivity and 30.8% specificity for the prediction of AKI using Acute Kidney Injury Network criteria and 89.3% sensitivity and 27.8% specificity when paired with the Risk, Injury, Failure, Loss, End Stage Renal Disease criteria. A receiver operating characteristic area under the curve analysis revealed a nonsignificant predictive ability of 55.8% (95% confidence interval 0.47-0.65) when RA was paired with Acute Kidney Injury ...Continue Reading

References

Aug 18, 2004·Critical Care : the Official Journal of the Critical Care Forum·Rinaldo BellomoUNKNOWN Acute Dialysis Quality Initiative workgroup
Nov 26, 2004·Journal of the American Society of Nephrology : JASN·Charuhas V ThakarEmil P Paganini
Jan 24, 2006·The Annals of Thoracic Surgery·Anne KuitunenVille Pettilä
Nov 8, 2006·Circulation·Rajendra H MehtaUNKNOWN Society of Thoracic Surgeons National Cardiac Surgery Database Investigators
Mar 3, 2007·Critical Care : the Official Journal of the Critical Care Forum·Ravindra L MehtaUNKNOWN Acute Kidney Injury Network
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Mitchell H Rosner, Mark D Okusa
Aug 5, 2008·Critical Care : the Official Journal of the Critical Care Forum·Michael HaaseAnja Haase-Fielitz
Aug 28, 2009·The New England Journal of Medicine·Till KellerStefan Blankenberg
Sep 29, 2009·Journal of Critical Care·Wendy LimDeborah Cook
Mar 20, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Stuart L Goldstein, Lakhmir S Chawla
Mar 27, 2010·The Annals of Thoracic Surgery·Madhav SwaminathanMark Stafford-Smith
Jul 29, 2010·Intensive Care Medicine·Brahim BenomarPierre Squara
Jan 15, 2011·Critical Care : the Official Journal of the Critical Care Forum·Lars EnglbergerHartzell V Schaff
Jul 21, 2011·Critical Care : the Official Journal of the Critical Care Forum·John R ProwleRinaldo Bellomo
Aug 13, 2011·Journal of the American Society of Nephrology : JASN·Chirag R ParikhUNKNOWN TRIBE-AKI Consortium
Jan 25, 2012·The Annals of Thoracic Surgery·Daisuke KatagiriEisei Noiri
Jun 6, 2013·Journal of Cardiothoracic and Vascular Anesthesia·David R McIlroyRobert N Sladen
Feb 1, 2014·Journal of the American Society of Nephrology : JASN·Gur P Kaushal, Sudhir V Shah
Mar 29, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Dinna N CruzUNKNOWN NEFROINT Investigators
Nov 28, 2014·Critical Care : the Official Journal of the Critical Care Forum·Xiaobo Yang, Bin Du
Dec 3, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·John W PickeringSuetonia C Palmer
Apr 19, 2015·Critical Care : the Official Journal of the Critical Care Forum·Lakhmir S ChawlaClaudio Ronco
Jul 26, 2015·The Annals of Thoracic Surgery·Theron A PaughUNKNOWN Perfusion Measures and Outcomes PERForm Registry
Nov 28, 2015·Clinical Kidney Journal·Gareth RobertsAled Phillips
Feb 26, 2016·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Shina MenonRajit K Basu
May 28, 2016·Critical Care : the Official Journal of the Critical Care Forum·Jochen MetzgerMatthias Klingele
Feb 1, 2013·Clinical Kidney Journal·José António Lopes, Sofia Jorge
Jun 19, 2017·Journal of Nephrology·Simona PozzoliPaolo Manunta

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Citations

Feb 7, 2020·The American Journal of Emergency Medicine·Holly R HansonRajit K Basu

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