PMID: 20630131Jul 16, 2010Paper

Renal artery revascularization in patients with atherosclerotic renal artery stenosis and impaired renal function: conservative management versus renal artery stenting

Clinical Nephrology
L E DichtelA J Peixoto

Abstract

The impact of percutaneous renal artery angioplasty and stenting (PTRAS) for treatment of atherosclerotic renal artery stenosis (ARAS) is not fully understood, especially in patients with chronic kidney disease (CKD). The goal of this study was to compare renal outcomes in patients treated with PTRAS with those managed conservatively. Retrospective cohort study of 118 prevalent patients with significant ARAS and moderate-to-severe CKD who were treated medically (n = 71) or with PTRAS (n = 47). The primary endpoint was change in renal function over the first year after diagnosis/treatment. Average age was 73 +/- 8 years, baseline glomerular filtration rate was 37 +/- 15 ml/min/1.73 m2, and average follow-up was 34 months. Baseline characteristics were similar between the two groups, with the exception of higher diastolic blood pressure in the PTRAS group (75 versus 70 mmHg, p = 0.028). There were no significant differences between the two groups during follow-up. The decline in glomerular filtration rate was similar in both groups (-1.6 ml/min/1.73 m2 in the medical group versus -1.4 ml/min/1.73 m2 in the PTRAS group, p = 0.938). Multivariate models did not indicate an association between treatment modality and changes in renal ...Continue Reading

Citations

Jul 15, 2011·Omics : a Journal of Integrative Biology·Mahmoud A GhannoumPatrick M Gillevet
Apr 20, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Paola CaielliGian Paolo Rossi
Dec 30, 2011·Current Cardiology Reports·Rajan A G Patel, Christopher J White
Jun 10, 2015·Nature Reviews. Nephrology·Olivier J WoutersAndrew S Narva
Jan 26, 2017·Renal Failure·Zeyuan LuFeng Wang
Feb 6, 2017·Current Hypertension Reports·Patricia Van der NiepenAlexandre Persu
Oct 7, 2017·American Journal of Hypertension·Sandra M Herrmann, Stephen C Textor
Sep 11, 2010·Expert Review of Cardiovascular Therapy·Aldo J PeixotoSergio F F Santos
Jul 30, 2011·Current Opinion in Cardiology·Pascal Meier
Jun 24, 2020·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yoshio Iwashima, Toshihiko Ishimitsu

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