Renal artery stenosis in aortoarteritis: spectrum of disease in children and adults

Kidney & Blood Pressure Research
P AroraA Kumar

Abstract

Nonspecific aortoarteritis is the commonest cause of renovascular hypertension (RVH) accounting for 87% of the patients in the present study. We compared the clinical and radiographic features and outcome in children (n = 16) and adult (n = 24) patients with aortoarteritis. Children have a shorter duration of disease and present more commonly with constitutional symptoms. All the patients were hypertensive; however, malignant hypertension and hypertensive encephalopathy were more common in children. Abdominal bruit and asymmetry of pulses were present only in 75 and 35% of the patients, respectively. Asymmetric kidney size on ultrasound was present in 15 of 24 adults, whereas 9 of 16 children had equal sized kidneys. Captopril renography had a better sensitivity for detection of RVH in children (13 of 16 in children vs. 12 of 24 in adults showing positive results). On intra-arterial digital substraction angiography, abdominal aortic involvement was invariable, whereas the thoracic aorta was involved less frequently in both age groups. Angiographic scores for the severity of vascular involvement was significantly lesser in children (6.87+/-4.8) as compared to adults (11.32+/-4.5). Thirteen of the 15 children were found suitable ...Continue Reading

Citations

Feb 1, 2012·European Journal of Pediatrics·Elżbieta SadurskaElżbieta Czekajska-Chehab
Mar 8, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kai KönigMartin B E Schneider
Sep 17, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Sameh AbdulsameaKjell Tullus
Oct 27, 2009·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kjell TullusStephen D Marks
Aug 13, 2003·The Journal of Urology·Anant Kumarraj Kumar Sharma
Apr 1, 2014·European Journal of Medical Research·Lian DuanZhiyong Liang
Feb 21, 2016·Journal of the American Society of Hypertension : JASH·Foteini ChristopoulouMoses Elisaf
May 15, 2007·Journal of Vascular and Interventional Radiology : JVIR·Richard B TowbinDerek J Roebuck

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