Renal cancer

Lancet
Umberto Capitanio, Francesco Montorsi

Abstract

The diagnosis and management of renal cell carcinoma have changed remarkably rapidly. Although the incidence of renal cell carcinoma has been increasing, survival has improved substantially. As incidental diagnosis of small indolent cancers has become more frequent, active surveillance, robot-assisted nephron-sparing surgical techniques, and minimally invasive procedures, such as thermal ablation, have gained popularity. Despite progression in cancer control and survival, locally advanced disease and distant metastases are still diagnosed in a notable proportion of patients. An integrated management strategy that includes surgical debulking and systemic treatment with well established targeted biological drugs has improved the care of patients. Nevertheless, uncertainties, controversies, and research questions remain. Further advances are expected from translational and clinical studies.

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Citations

Feb 13, 2016·EBioMedicine·Raffaele RattaGiuseppe Procopio
Mar 30, 2016·European Urology·Umberto CapitanioFrancesco Montorsi
Jul 2, 2016·World Journal of Urology·Umberto Capitanio, Bradley C Leibovich
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Jan 19, 2019·BJU International·Umberto CapitanioFrancesco Montorsi
Mar 16, 2019·Cell Death & Disease·Sifan YuJun Guo

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