Renal cell carcinoma and malignant phase hypertension

Blood Pressure
P S WongD G Beevers

Abstract

Many cross-sectional and follow-up studies of large numbers of patients with hypertension have demonstrated an increased prevalence and mortality from renal cancer. We report the details of three patients with renal cell carcinoma from a series of 254 consecutive patients with malignant phase hypertension, an excess over the expected number reported from several large published series with non-malignant hypertension. In view of this excess we investigated the prevalence of hypertension in a series of 192 consecutive patients who presented with a diagnosis of renal cell carcinoma, in comparison with a local unselected population screening survey. Hypertension was found in 43% of the renal carcinoma patients and 20% of the local population, also a clear excess. The mechanism of the association between renal cancer and malignant and non-malignant hypertension is unclear.

References

Oct 1, 1977·The Journal of Urology·A MelmanM H Weinberger
Jan 25, 1986·British Medical Journal·M E AhmedM Beevers
Mar 6, 1993·BMJ : British Medical Journal·D J HoleA F Lever
Mar 6, 1993·BMJ : British Medical Journal·A E FletcherJ Webster
Sep 1, 1996·Hypertension·P Hamet

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Citations

Apr 30, 2005·The Journal of Clinical Hypertension·Joel Handler
Apr 22, 2009·AJR. American Journal of Roentgenology·I-Chen TsaiClayton Chi-Chang Chen

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