Renal cell carcinoma of native kidneys: prospective study of 129 renal transplant patients

The Journal of Urology
J D DoubletJ D Sraer

Abstract

We evaluated the prevalence of renal cell carcinoma of the native kidneys in renal transplant recipients as well as possible risk factors. A total of 129 consecutive renal transplant recipients underwent ultrasound examination of the native kidneys as part of a routine evaluation. A record was made of acquired cystic kidney disease, defined as 3 cysts or more, and of suspicious masses. When a malignancy was suspected radical nephrectomy was performed. The overall prevalence of renal cell carcinoma of the native kidney was 5 in 129 recipients (3.9%). All cancers were limited to the kidney. No significant relationship was detected between renal cell carcinoma occurrence and patient age, dialysis (when initiated, type and duration), transplantation, drug regimen or incidence of acquired cystic kidney disease. The risk of renal cell carcinoma, a clinically significant cancer, was approximately 100 times greater in our renal transplant patients than in the general population but no significant risk factor could be identified. Routine ultrasonography for early diagnosis in asymptomatic patients on immunosuppressive therapy is strongly recommended to improve prognosis.

References

Apr 1, 1992·The Journal of Urology·P S ChandhokeM Rothstein
Nov 1, 1990·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·I IshikawaS Suzuki
Jan 1, 1989·American Journal of Nephrology·L R MillerM H Kutner
May 1, 1995·British Journal of Urology·R SchmidtM Pollok
Jun 1, 1994·Scandinavian Journal of Urology and Nephrology·A JekunenP Virkkunen
Sep 1, 1994·The Journal of Urology·Y TerasawaH Sekino
Jan 1, 1994·The Journal of Urology·L A Levine, B M Gburek

❮ Previous
Next ❯

Citations

Jan 22, 2004·Current Urology Reports·Matthew M CooneyNicholas J Vogelzang
May 16, 2002·Transplantation Proceedings·Jacek SzmidtM Lao
May 16, 2002·Transplantation Proceedings·W C NahasS Arap
Feb 27, 2003·Critical Reviews in Oncology/hematology·Cynthia L Martel, Primo N Lara
May 25, 2002·Kidney International·Mark D DentonNina Tolkoff-Rubin
Mar 13, 2003·Kidney International·Fu L LuanManikkam Suthanthiran
Mar 16, 2005·The American Journal of Surgical Pathology·Norbert SuleLuan D Truong
Jan 16, 2004·Transplantation·Morgan RouprêtArnaud Méjean
Oct 8, 2005·Transplantation·Barry D KahanCharles T Van Buren
Oct 8, 2005·Transplantation·S Mohamed MoudouniPhilippe Thibault
Oct 8, 2005·Transplantation·Nicolas A Muruve, Daniel A Shoskes
Dec 9, 2000·Transplant International : Official Journal of the European Society for Organ Transplantation·L KyllönenE Pukkala
Aug 20, 2011·Seminars in Dialysis·Swathi Singanamala, Ursula C Brewster
Mar 31, 2012·Archives of Pathology & Laboratory Medicine·Ying-Bei Chen, Satish K Tickoo
Jul 5, 2012·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Marek KarczewskiJacek Karczewski
Jan 15, 2014·Nature Reviews. Nephrology·Lin LiKamyar Kalantar-Zadeh
Apr 26, 2011·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·X TillouJ Petit
Feb 27, 2016·Transplantation Proceedings·A JakesS Bhandari
Oct 22, 2011·Urology·Ankur M ManvarMathew C Raynor
Jul 19, 2011·Hematology/oncology Clinics of North America·Eunyoung ChoPer Lindblad
May 18, 2011·The Journal of Urology·Michael LeveridgeAntonio Finelli
Oct 28, 2009·Transplantation Proceedings·X TillouJ Petit
Mar 27, 2007·Urology·Luiz Estevan IanhezMiguel Srougi
Feb 28, 2007·European Journal of Radiology·Jirí FerdaTomás Urge
Mar 27, 2015·Transplant International : Official Journal of the European Society for Organ Transplantation·Makoto RyosakaTsunenori Kondo
Oct 29, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Lisa NanovicR Michael Hofmann
May 15, 2004·Clinical Transplantation·Kenneth J McDonaldAlan G Jardine
Jan 21, 2004·Journal of Evaluation in Clinical Practice·W Adam Jurewicz, Andrew Miles
Aug 2, 2006·BJU International·Said M MoudouniJean-Dominique Doublet
Dec 8, 2011·Cancer Science·Toru InoueMasatsugu Moriyama
Oct 27, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A Goh, A Vathsala
Feb 20, 2013·Clinical Transplantation·Darden C SwordsRobert J Stratta
Sep 11, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·X TillouJ Petit
Jul 24, 2015·Journal of Nephrology·Giovanni M FrascàMaurizio Gallieni
Nov 3, 2005·Expert Opinion on Emerging Drugs·Philip E Shaheen, Ronald M Bukowski
Jun 20, 2015·Advances in Chronic Kidney Disease·Heather N Di Carlo, Frank S Darras
Feb 15, 2015·Insights Into Imaging·Ferruccio DegrassiMaria Assunta Cova
Jul 6, 2014·Actas urologicas españolas·O Rodríguez FabaH Villavicencio

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Polyendocrinopathies

Autoimmune polyendocrinopathies, also called polyglandular autoimmune syndromes (PGASs), or polyendocrine autoimmune syndromes(PASs), are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. Discover the latest research on autoimmune polyendocrinopathies here.

Autoimmune Polyendocrine Syndromes

This feed focuses on a rare genetic condition called Autoimmune Polyendocrine Syndromes, which are characterized by autoantibodies against multiple endocrine organs. This can lead to Type I Diabetes.

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.