Renal Cortical Necrosis in Postpartum Hemorrhage: A Case Series

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Marie FrimatAlexandre Hertig

Abstract

Pregnancy-related renal cortical necrosis may lead to end-stage renal disease. Although this obstetric complication had virtually disappeared in high-income countries, we have noted new cases in France over the past few years, all following postpartum hemorrhage. Case series. We retrospectively identified 18 patients from 5 French nephrology departments who developed renal cortical necrosis following postpartum hemorrhage in 2009 to 2013. Obstetric and renal features, therapeutic measures, and kidney disease outcome were studied. All patients had a severe postpartum hemorrhage (mean blood loss, 2.6±1.1 [SD] L). Hemodynamic instability and disseminated intravascular coagulation were reported in 5 and 11 patients, respectively. All developed rapid onset of acute kidney injury and required hemodialysis. Diagnosis of renal cortical necrosis was performed 4 to 33 days following delivery. At 6 months postpartum, 8 patients remained dialysis dependent and none recovered normal kidney function. The length of exposure to tranexamic acid treatment was significantly more prolonged in women whose estimated glomerular filtration rate remained <15mL/min/1.73m(2) (7.1±4.8 vs 2.9±2.4 hours; P=0.03). Retrospective study; small sample size. In t...Continue Reading

References

Feb 1, 1995·Anesthesiology·J C HorrowJ L Parmet
Apr 8, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·J R KooN H Won
Mar 31, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M FrançoisG Deray
Feb 24, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A R OdabaşU Coşkun
Mar 9, 2002·Journal of Computer Assisted Tomography·Jun Yong JeongChang Kyu Seong
Apr 24, 2003·Seminars in Thrombosis and Hemostasis·Margareta Hellgren
Apr 4, 2006·Lancet·Khalid S KhanPaul Fa Van Look
Feb 3, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jai PrakashR Raja
May 23, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·K S JosephUNKNOWN Maternal Health Study Group of the Canadian Perinatal Surveillance System
May 16, 2008·The New England Journal of Medicine·Dean A FergussonUNKNOWN BART Investigators
Jul 17, 2009·BMC Pregnancy and Childbirth·Pili FerrerHaleema Shakur
Feb 8, 2011·Expert Opinion on Pharmacotherapy·Panagiotis Peitsidis, Rezan A Kadir
Apr 19, 2011·Critical Care : the Official Journal of the Critical Care Forum·Anne-Sophie Ducloy-BouthorsSophie Susen
Oct 19, 2011·Archives of Surgery·Jonathan J MorrisonMark J Midwinter
Apr 25, 2012·Archives of Gynecology and Obstetrics·Carmelina GurrieriToby N Weingarten
Aug 11, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Fadi FakhouriVéronique Frémeaux-Bacchi
Oct 24, 2012·Obstetrics and Gynecology·William M CallaghanElena V Kuklina
Jul 3, 2013·Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia·Manisha SahayMichelle Padua
May 13, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Corinne DupontCyril Huissoud
Jul 9, 2014·Nature Reviews. Nephrology·Tinnakorn ChaiworapongsaRoberto Romero
Aug 1, 2014·BMJ : British Medical Journal·Azar MehrabadiUNKNOWN Canadian Perinatal Surveillance System Public Health Agency of Canada

❮ Previous
Next ❯

Citations

May 10, 2016·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Fadi Fakhouri
Feb 13, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Loïc SentilhesCatherine Deneux-Tharaux
Sep 9, 2017·Obstetrics and Gynecology·Luis D PachecoGeorge R Saade
Sep 29, 2017·Journal of Nephrology·Fadi Fakhouri, Clément Deltombe
Oct 13, 2017·Journal of Nephrology·Margarita Ibarra-HernándezGiorgina Barbara Piccoli
Apr 11, 2018·Journal of Nephrology·Patricia VillieAlexandre Hertig
Nov 22, 2018·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists, UNKNOWN Society for Maternal-Fetal Medicine
Jan 26, 2018·Medizinische Klinik, Intensivmedizin und Notfallmedizin·J WaskowskiF Stueber
Feb 26, 2019·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fleuria MeibodyAlexandre Hertig
Jun 10, 2017·Clinical Journal of the American Society of Nephrology : CJASN·Alexandra BruelFadi Fakhouri
Mar 22, 2019·Current Pharmaceutical Design·Jaclyn M PhillipsHoma K Ahmadzia
Jan 11, 2018·British Journal of Haematology·Stephen P HibbsBeverley J Hunt
Sep 11, 2019·Journal of Clinical Medicine·Angela VinturacheIngrid Watt-Coote
Jan 23, 2021·Scientific Reports·Paul SpieseckeMarkus H Lerchbaumer
Dec 21, 2020·European Journal of Clinical Pharmacology·Dominik StämpfliMichael Heesen
Jan 21, 2021·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Arnaud LechienPhilippe Van der Linden
May 7, 2021·Nature Reviews. Nephrology·Fadi Fakhouri, Véronique Frémeaux-Bacchi
Aug 6, 2021·Critical Care : the Official Journal of the Critical Care Forum·Sebastian ImachUNKNOWN TraumaRegister DGU
Aug 4, 2021·International Journal of Obstetric Anesthesia·A ShanderL Sentilhes
Mar 13, 2021·Case Reports in Nephrology and Dialysis·Yngvar Lunde HaaskjoldRannveig Skrunes

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