PMID: 7334747Dec 1, 1981Paper

Renal function in acute febrile urinary tract infection in children: pathophysiologic aspects on the reduced concentrating capacity

Kidney International
U Berg

Abstract

In an attempt to elucidate the reduced concentrating capacity in acute pyelonephritis, we studied the renal function in 14 children, 5 to 16 years of age. Clearance of inulin, PAH, and free water, urinary sodium excretion, and maximal urine osmolality after 18 hours of thirst have been determined at and within 10 months after infection. Glomerular filtration rate and renal plasma flow were found to be increased during infection and normalized after infection. Urinary sodium excretion, distal sodium delivery, and maximal urine osmolality were decreased during infection and increased afterwards. Kidney size was also increased during infection. It is postulated that the reduced concentrating capacity is due to a washout effect mediated by an increased medullary blood flow and to a low distal tubular sodium delivery.

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Citations

Jul 1, 1992·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·B JakobssonU Berg
Dec 31, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Elena A RodionovaMarina Zelenina
Aug 1, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Se Jin ParkKee Hyuck Kim
Aug 1, 1989·The Journal of Pediatrics·B StrandvikE Kusoffsky
May 1, 1992·Acta Paediatrica·J Rodríguez-SorianoM Ubetagoyena
Dec 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·P De ManC Svanborg
Dec 1, 1983·Archives of Disease in Childhood·U B Berg, S B Johansson
Nov 1, 1988·Archives of Disease in Childhood·B JohanssonU Berg
Jan 1, 1991·Scandinavian Journal of Urology and Nephrology·T Sandberg
Jan 1, 1991·Scandinavian Journal of Urology and Nephrology·G Sterner
Mar 1, 1991·Kidney International·C SvanborgT Sandberg
Dec 25, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Anna BertiniSebastiano A G Lava
Dec 14, 2007·Acta Paediatrica·Víctor M García NietoEduardo H Garin
Mar 4, 2011·Pediatric Blood & Cancer·Lars HjorthDiana Karpman
Sep 1, 1982·Acta paediatrica Scandinavica·U BergB Strandvik
Apr 24, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Ulla B BergJonas Björk
Aug 19, 2010·Annals of Saudi Medicine·Aftab S ChishtiStefan G Kiessling
Feb 2, 2019·European Journal of Pediatrics·Víctor García-NietoEduardo H Garin
May 13, 2021·American Journal of Physiology. Cell Physiology·Helle Praetorius

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