PMID: 2501970May 1, 1989

Renal function in chronic lithium-treated patients

Acta Psychiatrica Scandinavica
G ConteE Sacchetti


We investigated the renal function (urine volume, glomerular filtration rate, urinary osmolality and proteinuria) of 50 patients chronically treated with lithium carbonate for major affective disorder. No patient had any alteration in the parameters considered. No relationship was found between any of the parameters studied and duration of illness or lithium levels, both in serum and red blood cells. These results were confirmed by the administration of the DDAVP test to 10 patients of the original sample; no alteration of concentration ability was found. We suggest that the discrepancy between our findings and those of most authors was a result of the serum lithium level of our patient sample, which was lower than that usually used in other studies.


Jun 2, 1979·British Medical Journal·R P HullinD B Morgan
Nov 1, 1987·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R BotonD C Batlle
Jan 1, 1987·Acta Psychiatrica Scandinavica·A J GelenbergB J Kerman
Apr 1, 1985·Acta Psychiatrica Scandinavica·H LøkkegaardK Rasmussen
Jan 1, 1984·Neuropsychobiology·L SmiganA Wahlin
Jan 1, 1981·Psychopharmacology·P Vestergaard, K Thomsen
Jan 1, 1983·Acta Psychiatrica Scandinavica·P Vestergaard, A Amdisen


May 10, 2002·Progress in Neuro-psychopharmacology & Biological Psychiatry·Tayfun TuranFahrettin Keleştimur
Dec 31, 1997·Journal of Clinical Psychopharmacology·S Chugh, H Yager
Feb 1, 1993·Acta Psychiatrica Scandinavica·C O'DonovanR Bowen

Related Concepts

Manic Disorder
Adiuretin SD
Kidney Function Tests
Long-term Care

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.