PMID: 1986982Jan 1, 1991

Renal manifestations of NaCl sensitivity in borderline hypertensive rats

Hypertension
G F DiBona, S Y Jones

Abstract

Compared with the normotensive Wistar-Kyoto rat, the spontaneously hypertensive rat exhibits exaggerated alterations in renal sympathetic nerve activity and excretory function during volume expansion (exaggerated natriuresis) and environmental stress (antinatriuresis). The borderline hypertensive rat is the first filial offspring of the spontaneously hypertensive rat and the Wistar-Kyoto rat and develops hypertension with increased dietary NaCl intake. The present investigation sought to determine whether the dietary NaCl intake-induced transition from the normotensive state of the Wistar-Kyoto parent to the hypertensive state of the spontaneously hypertensive parent in the borderline hypertensive rat was accompanied by a similar transition of the renal sympathetic nerve activity and excretory responses to volume expansion and environmental stress. Borderline hypertensive rats fed a 1% NaCl diet remained normotensive and exhibited renal sympathetic nerve activity and excretory responses to volume expansion and environmental stress that were similar to those of their Wistar-Kyoto parent. Borderline hypertensive rats fed an 8% NaCl diet developed hypertension and exhibited responses that were similar to those of their spontaneous...Continue Reading

References

Jun 1, 1989·American Journal of Hypertension·S OparilY F Chen
Jan 1, 1989·Clinical and Experimental Hypertension. Part A, Theory and Practice·J E LawlerP G Baer
Sep 1, 1988·The American Journal of Physiology·B J SandersJ E Lawler
Jan 1, 1987·Clinical and Experimental Hypertension. Part A, Theory and Practice·J E LawlerS Oparil
May 1, 1986·Proceedings of the Society for Experimental Biology and Medicine·G F DiBona, L L Sawin
Apr 1, 1982·Physiological Reviews·B Folkow
Jun 1, 1981·Acta Physiologica Scandinavica·S E RickstenP Thorén
Jul 1, 1980·Circulation Research·S WallensteinJ L Fleiss

Citations

Feb 20, 1998·Physiology & Behavior·R P SoltisM R Smith
Jul 24, 2010·Journal of Applied Physiology·Michael J Kenney
Aug 1, 1997·Journal of Hypertension·H C DeterA M Sharma
Jan 1, 1992·Neuroscience and Biobehavioral Reviews·B J Sanders, J E Lawler
Apr 1, 1995·Hypertension·G F DiBona, S Y Jones
Jan 1, 1992·Hypertension·G F DiBona, S Y Jones
Sep 1, 1992·Hypertension·S R Reddy, T A Kotchen
Feb 1, 1993·Hypertension·G F DiBona, S Y Jones
Mar 8, 2003·Hypertension·G F DiBona
Dec 26, 2001·Hypertension·K BuchholzH C Deter
Aug 19, 2004·The American Journal of Chinese Medicine·Shu-Yun ZhengJian-Guo Xu
Jul 1, 1995·Psychosomatic Medicine·D E AndersonJ L Austin
Nov 9, 2014·Applied Biochemistry and Biotechnology·Jianxin LiQunce Huang
Mar 1, 1994·Journal of the Experimental Analysis of Behavior·J S Turkkan
Mar 23, 2011·Experimental Physiology·Olivera SarenacNina Japundzić-Zigon
May 18, 2020·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Bojana SavićNina Japundzić-Zigon

Related Concepts

Denervation
Glomerular Filtration Rate
Hypertensive Disease
Kidney
Natriuresis
Rats, Inbred SHR
Rats, Inbred WKY
Renal Blood Flow
Sodium, Dietary
Mental Suffering

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