PMID: 8612436Sep 1, 1995Paper

Renal, metabolic, and hormonal responses to proteins of different origin in normotensive, nonproteinuric type I diabetic patients

Diabetes Care
P KontessisA Souvatzoglou

Abstract

Whether the differences in renal function found in vegetarian compared with omnivorous subjects are related to quantity or quality of the protein is unknown. We have studied the renal function of nine normotensive, nonproteinuric type I diabetic patients who were fed in random order for 4 weeks either an animal protein diet (APD) (protein intake 1.1 g . kg-1 . day-1) or a vegetable protein diet VPD (protein intake 0.95 g . kg-1 . day-1). The two diets were isocaloric. In a crossover study, we measured glomerular filtration rate (GFR) (inulin clearance), renal plasma flow (RPF) (p-aminohippurate clearance), plasma amino acids, growth hormone, glucagon, insulin-like growth factor I-(IGF-I), and microalbuminuria. GFR and RPF were lower with the VPD than with the APD (89.9 +/- 4.1 vs. 105.6 +/- 5.1 ml . min-1 . 1.73 m-2, P < 0.05, and 425.7 +/- 22.2 vs. 477.8 +/- 32.2 ml . min-1 1.73m-2, P < 0.05, respectively). Renal vascular resistance (RVR) was higher with the VPD than with the APD (101 +/- 25 vs. 91 +/- 10 mmHg . min-1 . ml-1, P < 0.05). Filtration fraction (FF) remained unchanged after either diet. Fractional clearance of albumin fell with the VPD to 2.0 +/- 0.65 from 3.4 +/- 1.15 x 10-6 (P < 0.05). At the end of the APD and V...Continue Reading

Citations

Sep 17, 2003·Current Diabetes Reports·Marion J Franz, Madelyn L Wheeler
Apr 9, 2008·The British Journal of Nutrition·Claudio Maffeis, Leonardo Pinelli
Mar 26, 2003·The British Journal of Nutrition·Shu-Tzu ChenJiun-Rong Chen
Mar 1, 2011·Metabolic Syndrome and Related Disorders·Gema SoutoMaria M Adeva
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Young Eun ChoiKyung Ah Park
Aug 1, 2010·Nutrients·Mark Messina, Virginia Messina
Jun 5, 2003·Journal of the American Dietetic Association·UNKNOWN American Dietetic Association, UNKNOWN Dietitians of Canada
Jun 27, 2003·Canadian Journal of Dietetic Practice and Research : a Publication of Dietitians of Canada = Revue Canadienne De La Pratique Et De La Recherche En Diététique : Une Publication Des Diététistes Du Canada·UNKNOWN American Dietetic Association, UNKNOWN Dietitians of Canada
Oct 22, 2014·Nature Reviews. Nephrology·Nishank Jain, Robert F Reilly
Sep 28, 2013·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Philippe ChauveauMichel Aparicio
Jul 3, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Alex ChangLawrence J Appel
Feb 2, 2010·Seminars in Nephrology·M Krishna Mani
Sep 18, 2009·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Leila Azadbakht, Ahmad Esmaillzadeh
Jul 28, 2007·The Journal of Nutritional Biochemistry·Sun-Young HwangHarold M Aukema
Apr 23, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Alex ChangHolly Kramer
Mar 27, 2007·Journal of the American Dietetic Association·Adam M BernsteinZhaoping Li
Apr 28, 2005·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·J I MannUNKNOWN Diabetes and Nutrition Study Group (DNSG) of the European Association
Aug 2, 2005·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·Christina A HedmanHans J Arnqvist
May 25, 2011·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Katarzyna MitręgaTadeusz F Krzemiński
Apr 13, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·María M Adeva, Gema Souto
Feb 21, 2002·The Diabetes Educator·Patty Rais-Keeley
Mar 22, 2016·Physiological Reports·Karianna F M Teunissen-BeekmanMarleen A van Baak
May 7, 2016·World Journal of Nephrology·Nancy J McGrawAlan R Parrish
Jan 24, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Emad YuzbashianFereidoun Azizi
Jan 16, 2019·Annals of the New York Academy of Sciences·Nia S MitchellWilliam S Yancy
Jul 10, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Philippe ChauveauMichel Aparicio
Nov 2, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Minesh KhatriMitchell S V Elkind
Nov 14, 1997·The Diabetes Educator·M J Franz
Dec 10, 1999·Diabetes/metabolism Research and Reviews·C S Bartsocas
Mar 7, 2000·The Journal of Nutrition·G CasoF Contaldo
Jun 13, 2020·Nature Reviews. Nephrology·Juan J CarreroDenis Fouque
Dec 17, 2005·Arquivos brasileiros de endocrinologia e metabologia·Vanessa D F de MelloJorge L Gross
Jun 7, 2019·Nutrients·Aleix CasesEmilio Gonzalez-Parra
Jul 14, 2001·The American Journal of Clinical Nutrition·D J JenkinsP W Connelly
Jan 12, 2021·Frontiers in Medicine·Adamasco CupistiGiorgina B Piccoli

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