PMID: 9170023Apr 1, 1997Paper

Renal potassium wasting and hypocalciuria ameliorated with magnesium repletion in Gitelman's syndrome

Journal of Korean Medical Science
Y J ChoH J Kim

Abstract

A woman aged 45 years was presented with hypokalemic metabolic alkalosis and hypomagnesemia associated with renal potassium and magnesium wasting. Her 24-hour urinary calcium excretion was strikingly low despite normocalcemia and normal creatinine clearance, which is one of characteristic findings of Gitelman's syndrome (GS). She was evaluated for the responses following Mg supplementation for 10 days, which showed marked increments in serum potassium and magnesium as well as improvements of the degree of renal potassium wasting and hypocalciuria. This amelioration of abnormal biochemical pictures in this patient after Mg supplementation proposes that the hypokalemia with renal potassium wasting and hypocalciuria may be caused by abnormal Mg metabolism.

Citations

Jul 13, 2004·Journal of Cardiac Surgery·Tirone E DavidSusan Armstrong
Nov 30, 2006·Asian Cardiovascular & Thoracic Annals·Alireza A GhavidelKamal Raesi
Nov 13, 2007·Technology in Cancer Research & Treatment·B HanJ C Bischof

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