PMID: 376809Aug 1, 1979Paper

Renal retransplantation in children

The Journal of Pediatrics
R N FineB M Korsch

Abstract

Evaluation of 75 cadaver donor retransplants revealed that the primary factor influencing allograft survival is patient responsiveness as reflected by sensitization with preformed cytotoxic antibodies. Actuarial allograft survival rates for nonpresensitized (less than 5%) and moderately presensitized (5 to 50%) recipients were significantly (P less than 0.01) better than those of highly presensitized (greater than 50%) recipients. Although HLA A&B antigen histocompatibility did not have a statistically significant effect on retransplant outcome, it appeared to influence allograft survival in the highly presensitized recipient. An approach to the management of children who lose an initial or subsequent allograft is indicated by these data.

References

Oct 1, 1977·The American Journal of Medicine·M H MalekzadehR H Fine
Aug 24, 1978·The New England Journal of Medicine·G Opelz, P I Terasaki
Nov 10, 1972·Science·G OpelzP I Terasaki
Apr 1, 1974·Archives of Surgery·B S Husberg, T E Starzl
Jul 15, 1971·The New England Journal of Medicine·J C PierceD M Hume

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Citations

Oct 14, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Jenni MiettinenHannu Jalanko
Apr 1, 2006·Pediatric Transplantation·Alin L GirnitaAdriana Zeevi
May 9, 2006·Pediatric Transplantation·Hubert WongGuido Filler
May 1, 1985·Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine·N Delmar-McClure
Nov 1, 1981·Acta paediatrica Scandinavica·I OzalpK Yalaz
Feb 1, 1990·The Journal of Urology·B M ChurchillP A Merguerian

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