journal cover

Renal toxicity of aspirin to rats pre-treated with ethinyl oestradiol

Toxicology Letters

Mar 1, 1980

R A Owen, R Heywood

PMID: 7466856

Abstract

Castrated rats receiving aspirin at a dose level of 1000 mg/kg showed necrosis of the proximal convoluted tubules, similar to that seen in female rats, and the extent of this lesion was increased by oestrogen pre-treatment. Urinary gamma-glutamyl transpeptidase activity was a useful ind...read more

Mentioned in this Paper

Necrosis
Urine
Toxic Nephropathy
Estradiol Measurement
Kidney
Gamma-glutamyltransferase Activity
Zorprin
Estradiol
Progynon C
Estrogens
Paper Details
References
  • References5
  • Citations2
1
  • References5
  • Citations2
1

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

GTPases in Intracellular Trafficking

GTPases, including small ras sub-families and large dynamin are regulators of intracellular trafficking. They are implicated in vesicular transport and important for the communication within cells. Discover the latest search on GTPases in intracellular trafficking here.

Coronavirus

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the Middle East Respiratory Syndrome, Severe Acute Respiratory Syndrome, and 2019-nCov. Coronaviruses can spread from animals to humans. Symptoms include fever, cough, shortness of breath, and breathing difficulties. In more severe cases, it can lead to death. Here is the latest research on coronaviruses.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Membranoproliferative Glomerulonephritis

Membranoproliferative glomerulonephritis is type of Chronic glomerulonephritis characterized histologically by proliferation of mesangial cells, increase in the mesangial extracellular matrix, and a thickening of the glomerular capillary walls. Discover the latest research on membranoproliferative glomerulonephritis here.

Severe Acute Respiratory Syndrome

Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the SARS coronavirus (SARS-CoV). Initial symptoms are flu-like and may include fever, muscle pain, lethargy symptoms, cough, sore throat, and other nonspecific symptoms. SARS may eventually lead to shortness of breath and pneumonia; either direct viral pneumonia or secondary bacterial pneumonia. DIscover the latest research on SARS here.

Microbiome and MS

Multiple sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system which is characterized by inflammatory demyelination and neurodegeneration. Here is the latest research on the influence of the human microbiome on this dymyelinating disorder.

Notch-Instructed 3D Cancer Genomes (Keystone)

Cancer genomics employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. This feed focuses on Notch-instructed 3D cancer genomes. Discover the latest research here.

© 2020 Meta ULC. All rights reserved

Renal toxicity of aspirin to rats pre-treated with ethinyl oestradiol

Toxicology Letters

Mar 1, 1980

R A Owen, R Heywood

PMID: 7466856

DOI:

Abstract

Castrated rats receiving aspirin at a dose level of 1000 mg/kg showed necrosis of the proximal convoluted tubules, similar to that seen in female rats, and the extent of this lesion was increased by oestrogen pre-treatment. Urinary gamma-glutamyl transpeptidase activity was a useful ind...read more

Mentioned in this Paper

Necrosis
Urine
Toxic Nephropathy
Estradiol Measurement
Kidney
Gamma-glutamyltransferase Activity
Zorprin
Estradiol
Progynon C
Estrogens

Trending Feeds

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Toxicology and Applied Pharmacology

Binding of hexachlorobutadiene to alpha 2u-globulin and its role in nephrotoxicity in rats

Toxicology and Applied PharmacologyJanuary 24, 1998
A PählerW Dekant
Paper Details
References
  • References5
  • Citations2
1
  • References5
  • Citations2
1
/papers/renal-toxicity-of-aspirin-to-rats-pre-treated/7466856