Renal transplantation in adults with Henoch-Schonlein purpura: long-term outcome

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Gabriella MoroniPiergiorgio Messa

Abstract

Little information is available about the long-term outcome of renal transplantation in adults with Henoch-Schonlein purpura (HSP). We compared the outcomes of 17 patients with HSP who received 19 renal transplants with those of 38 controls matched for time of transplantation, age, gender and source of donor. The mean post-transplant follow-up was 109 +/- 99 months for HSP patients and 110 +/- 78 months for controls. The actuarial 15-year patient survival was 80% in HSP patients and 82% in controls, and the death-censored graft survival was 64% in HSP patients and in controls. The risks of acute rejection, chronic graft dysfunction, arterial hypertension and infection were not different between the two groups. In eight grafts (42%) recurrence of HSP nephritis was found (0.05/patient/year). In spite of therapy, one patient died and four eventually restarted dialysis respectively 10, 32, 35 and 143 months after renal transplant. Seventy-one percent of grafts transplanted in patients with necrotizing/crescentic glomerulonephritis of the native kidney had HSP recurrence in comparison to 12% of recurrences in patients with mesangial nephritis (P = 0.05) Long-term patient and allograft survival of HSP patients was good. However, 42% ...Continue Reading

References

Aug 1, 1975·The American Journal of Medicine·T H MathewP Kincaid-Smith
Jan 1, 1987·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·C C NastA H Cohen
Nov 1, 1982·Transplantation·J S Cameron
May 15, 1997·Transplantation·G NybergJ Wieslander
Dec 10, 1999·Journal of the American Society of Nephrology : JASN·A RaiS Adler
Feb 7, 2001·Journal of the American Society of Nephrology : JASN·Steven James Chadban
Nov 13, 2001·Kidney International·C PonticelliA Tarantino
Jul 12, 2002·The New England Journal of Medicine·Esther M BrigantiSteven J Chadban
May 30, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rosanna CoppoLeonardo Cagnoli
Mar 14, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·K SolezJ J Weening

❮ Previous
Next ❯

Citations

Jun 28, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Joyce P SamuelMichael C Braun
Aug 21, 2013·Transplantation Reviews·Ben Sprangers, Dirk R Kuypers
Apr 7, 2009·Néphrologie & thérapeutique·Evangeline PilleboutEric Thervet
Apr 29, 2015·Nature Reviews. Nephrology·Justine Bacchetta, Pierre Cochat
Apr 16, 2014·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Martin Pohl
Sep 30, 2016·Clinical and Experimental Nephrology·Mayuko KawabeUNKNOWN Japan Academic Consortium of Kidney Transplantation (JACK)
Jul 4, 2018·Nephrology·Izumi YamamotoTakashi Yokoo
Apr 16, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Claudio PonticelliRichard J Glassock
Jul 8, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Nada KanaanYves Pirson
Jul 29, 2010·Renal Failure·Catharina VonendSamuel S Weinstein
Oct 19, 2017·International Urology and Nephrology·Safak MiriogluMehmet Sukru Sever

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Aisling E CourtneyAlexander Peter Maxwell
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
K OkaS Takahara
© 2022 Meta ULC. All rights reserved